SUMMARY Joint capsule, meniscus, and cartilage from the patella and medial femoral condyle from 30 non-selected autopsies have been investigated for amyloid deposits with light and electron microscopy. Both right and left knee joints from 28 of the 30 autopsy specimens contained amyloid deposits (93%). The amyloid characteristically showed green dichroism in polarised light after staining with alkaline Congo red. The ultrastructural features were also characteristic of amyloid. Amyloid in capsule tissue was found in a subsynovial location, as well as deeper in the capsule tissue, while in the cartilage amyloid was localised along the surface. The meniscus tissue, in particular, contained heavy deposits of amyloid-mainly along the inner margin. Osteoarthritic changes, with fibrillation of the cartilage, were significantly related to amyloid deposition. No pathogenetic correlation between the osteoarthritic changes and amyloid deposition could be shown in the present investigation.
We describe three cases of xanthogranulomatous inflammation in the female genital tract—one affecting endometrium, tube and ovary, one affecting tube, ovary and parametrium and one confined to the endometrium. To date, xanthogranulomatous inflammation in the female genital tract has been reported in a total of 19 cases including the present three. The inflammation most often affects the endometrium but involvement of the vagina, cervix, fallopian tube and ovary may also occur.
The material comprises 225 patients. In 79 patients 35.1%) the tumour was closely excised and in a few cases biopsied before the patients underwent radical surgery. 146 patients were radically operated primarily. These two groups of patients are comparable with regard to sex, distribution of tumours on anatomical sites and the distribution of tumours with a given histological classification. We have ascertained that neither excision biopsy nor non-radical operation influences the prognosis if followed by radical operation within about 3 weeks.
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