continuously starting 15 min before sedation until 15 min after the endoscopy. In addition, plasma ca-Hypoventilation as a consequence of deep intravenous techolamine concentrations were determined. The sedation is the most frequently reported cause of results of this study are consistent with previous recardiac arrest during upper gastrointestinal endoports that cardiopulmonary events may occur during scopy (UGIE). Haemodynamic stress can contribute endoscopy, with or without sedation. Both midazolam to myocardial ischaemia; therefore, this study was and propofol sedation may provide some protection designed to observe prospectively the cardioagainst haemodynamic stress in response to insertion respiratory changes during UGIE using either miand manipulation of the endoscope, but sedation can dazolam or propofol for conscious sedation. Thirtyalso contribute to the occurrence of hypoxaemia. four patients, aged 50 years and older, ASA physical status I-III, scheduled for elective UGIE with sedation, Keywords: conscious sedation, midazolam, propofol;upper gastrointestinal endoscopy, cardiorespiratory were studied. Oxygen saturation, heart rate, non-invasive blood pressure and Holter ECG were recorded changes, catecholamine release.
Patients and methodsischaemia may result [3-5]. Forty consecutive patients, aged 50 years and older, ASA physical status I-III, scheduled for elective UGIE Accepted March 1998 Correspondence: V. L. B. Oei-Lim.with sedation, were studied. Data from six patients
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