1998 amide formation, amide hydrolysis amide formation, amide hydrolysis O 0320
-058Rapid Synthesis of Aliphatic Amides by Reaction of Carboxylic Acids, Grignard Reagent, and Amines: Application to the Preparation of [ 11 C]Amides.-Grignard reagents promote the reaction of simple carboxylic acids with aliphatic amines. The amides (III) are obtained in moderate to good yields in a short time (5-60 min). The reaction conditions are successfully applied to the synthesis of 11 C-labeled amides. -(AUBERT, C.; HUARD-PERRIO, C.; LASNE, M.-C.; J.
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