Peripheral blood leucocytes from 30 grossly anaemic professional blood donors
were investigated for phagocytosis, intracellular killing and chemotaxis. The nitro-blue tétrazolium
test was positive in 29 donors and negative in 1. Professional donors’ cells in the presence
of normal plasma were unable to phagocytose successfully and Candida killing and
opsonization were defective when donors’ plasma was used in the presence of normal cells
Chemotaxis of professional donors’ cells to Ag/Ab-treated normal plasma was reduced as was
chemotactic activity of normal cells in both Ag/Ab- and LPS-treated professional donors’
plasma.
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