OBJECTIVE: to assess the clinical effect of topical treatment using Ulmo honey associated
with oral ascorbic acid in patients with venous ulcers. METHOD: longitudinal and descriptive quantitative study. During one year, 18 patients
were assessed who were clinically diagnosed with venous ulcer in different stages,
male and female, adult, with a mean injury time of 13 months. Ulmo honey was
topically applied daily. The dressing was applied in accordance with the technical
standard for advanced dressings, combined with the daily oral consumptions of 500
mg of ascorbic acid. The monitoring instrument is the assessment table of venous
ulcers. RESULTS: full healing was achieved in 100% of the venous ulcers. No signs of complications
were observed, such as allergies or infection. CONCLUSION: the proposed treatment showed excellent clinical results for the healing of
venous ulcers. The honey demonstrated debriding and non-adherent properties, was
easy to apply and remove and was well accepted by the users. The described results
generated a research line on chronic wound treatment.
Myocardial autonomic denervation occurs after acute MI. This process is followed by a reduction of heart rate variability (HRV) and an increase of malignant ventricular arrhythmias and sudden death. This study investigated whether there are any significant differences in HRV among the population of MI who did and did not have malignant ventricular arrhythmias (MVAs), normal subjects and heart transplant recipients, the paradigm of the denervated heart. We studied 25 subjects aged 42 +/- 17 years, with normal clinical and cardiac noninvasive evaluation (group A); 70 patients aged 57 +/- 14 years, who had MI but no arrhythmic event in 36 months of follow-up (group B); 13 patients with MI aged 65 +/- 9 years, who had had sustained VT, VF, or sudden death (group C); and 16 cardiac transplant recipients aged 35 +/- 14 years (group D). The ECG was sampled for 256 seconds. We calculated, in time and frequency domain, the standard deviation of the RR cycle length and the spectral component's very low frequency (< 0.05 Hz), low frequency (0.05-0.15 Hz), and high frequency (0.15-0.35 Hz). The values of HRV in group A were significantly greater than in groups B, C, and D (P < 0.001) and greater in group B than in groups C and D (P < 0.001). Groups C and D did not differ (P = 0.610). These data indicate that HRV of patients who have had an MI and MVAs is very similar to that of heart transplant recipients. This is an indirect evidence that myocardial autonomic denervation may play an important role in the genesis of malignant arrhythmic events.
El objetivo de este estudio longitudinal fue validar clínica y planimétricamente la cicatrización de úlceras venosas con un prototipo de miel médica suplementada, nativa de Chile. La cicatrización de la úlcera venosa, demanda recursos sanitarios y tiempo de enfermería. Las terapias naturales, como la miel, son consideradas cicatrizantes, siendo el enfermero/a el profesional encargado de
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