Brighton BN1 9QJReaction of phenylmagnesium bromide with excess of sulphuryl chloride in ether-hexane at 0' gives benzenesulphonyl chloride and bromide in a combined yield of at least 58%. Substituted sulphonyl halides, YC6H4*S02X (Y = o-Me, rn-Me, rn-CI, and rn-CF,), are produced similarly in comparable yields. Diphenylmagnesium. diphenylcadmium, or phenyl-lithium under similar conditions give somewhat smaller yields of benzenesulphonyl halides. Use of arylmagnesium chlorides, ArMgCi (Ar = Ph, o-MeO-C6H,, p-Me,Si*C,H,, and c6cI,), in tetrahydrofuran-hexane at 0' gives pure arenesulphonyl chlorides in yields of 53-64%.Reactions of phenylethynylmagnesium chloride and of some benzylmagnesium chlorides with sulphuryl chloride in ether-hexane have also been studied.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.