A recently repor1t.d dlsease s y n d~o m e of Penaeus monodon In Thalland IS called 'yellow-head' or hua leung In Thal It is usually charactenzed by llght yellow coloratlon of the dorsal cephalothorax area and generally pale or bleached appearance of a f f~c t e d prawns The yellow color In the cephalothorav reglon iesults from the underlying y e l l o~~ hepatopancreas showlng through the translucent carapace In m o~i b u n d shrimp In h~stological prepdrations of moribund yellow-head specimens for the light mlcloscope. no consistent bacteiial fungal or parasltlc agents could be found The lylnphold organs ot yellow-head specimens sho\ved extensive abnormalities These Included obv~ously necrotlc cells and vacuolated cells with hypertrophied nuciel Also evldent were vely densely basophil~c, globose cytoplasmic ~nclusions located adjacent to some ot the hypertroph~ed nuclei Slrn~lar basophil~c inclusions were found In interst~tl~il hepatopancreat~c tissue In connective tlssue u n d e~ lylng the mld gut, In cardlac tissue, In glll t~s s u e and In hematopoetlc tissue T l a n s m~s s~o n electron mlclographs revealed the presence of pic\iously undescrlbed rod-shaped, enveloped virions in the cytoplasm adjacent to the nuclei of cells f~ om various tissues Free vlnons \yere also present In intercellular spaces The virions were s~r n d a to those of the ~tlsect grahulosls vlruses (Baculov~r~dae) In terms of cytoplasmic locatlon size, morphology and development. However, they were not occluded by granulln
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