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These results support the reliability of sentinel node biopsy in OSCC. Presurgical lymphoscintigraphy is essential, because it can modify the surgical procedure.

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with an absence of consensus, physicians with lower risk aversion more often recommended surgery compared to those with higher risk aversion (OR¼1.88, P¼0.052). When the vignette corresponded to a clinical case for which there is a surgical consensus decision, the unmarried male male manual worker has a 75% lower chance of being offered surgery compared to the married male small business owner (OR¼0.25, P¼0.024). We did not observe any differences based on the gender of the patient.Conclusions: Patients' socioeconomic status did affect clinical management decisions in head and neck oncology. The significant association between medical decision and individual behavioural characteristics of the physician documented still understudied mechanisms that involved nonbiological factors to variations in clinical practice.Clinical trial identification: NCT03663985.

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We aimed to identify factors for malignant transformation of oral lichen planus to oral cancer in order to inform the different specialists undertaking their clinical management. A retrospective cohort of biopsy-confirmed oral lichen planus consecutively diagnosed in 1995–2014 and followed-up until 2017 was selected. Demographic, clinical and follow-up information was collected. Multivariate Cox proportional-hazards models were performed to evaluate clinical and pathological factors associated with progression to oral cancer. The study included 257 oral lichen planus of which 5.4% progressed to oral cancer. Men and women differed in tobacco and alcohol consumption, and patients with and without described clinical aspect differed in diagnostic period, alcohol consumption and treatment. Alcohol consumption, tongue site, oldest diagnostic period and surgery as a type of treatment were independent prognostic factors for progression. This large non-selected retrospective cohort of oral lichen planus underscores the existing limitations of the current standard-of-care of such lesions. Well-designed, robust prospective studies and multidisciplinary treatment guidelines are warranted.