Patients with early gastric cancer who received H. pylori treatment had lower rates of metachronous gastric cancer and more improvement from baseline in the grade of gastric corpus atrophy than patients who received placebo. (Funded by the National Cancer Center, South Korea; ClinicalTrials.gov number, NCT02407119 .).
Comparison of LADG to ODG in patients with early gastric cancer resulted in improved QOL outcomes in the patients followed for up to 3 months in the LADG group.
N OFFSPRING REPORT OF A positive parental history of c a r d i o v a s c u l a r d i s e a s e (CVD), particularly if premature at onset, is a widely accepted risk factor for offspring cardiovascular events. Current guidelines 1,2 recommend consideration of a positive parental history of premature coronary heart disease when deciding whether to initiate antihyperlipidemic or antihypertensive therapy for primary prevention. However, the true magnitude of independent risk that is conferred by the occurrence of parental CVD remains controversial. This uncertainty exists in large part because available data examining the association between parental and offspring CVD are derived from retrospective casecontrol studies 3-7 or longitudinal studies 8-20 relying on offspring self-report, with limited or absent validation of parental events. Offspring report of parental history may be highly unreliable, 21-25 in part due to recall bias, and may lead to inflated estimates of risk associated with parental CVD. The effect
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