Established by the U.S. Green Building Council (USGBC), the Leadership in Energy and Environmental Design (LEED) became a sustainable leader of green building rating systems in American and many other countries. In Vietnam, LEED is expected as a potential solution in improving the sustainable quality of buildings for residents and solving the housing/infrastructure demand with a limit in resource consumption and minimizing negative environmental impacts. The study analyzed the awarded LEED 2009 credits by investigating the data of 36 of the total 42 LEED BC+D 2009 certified projects in Vietnam. The results of the investigation indicated the awarded credits were significantly implemented in Vietnam. These results were converted based on the summary updated on LEED version 4 of the USGBC report, to become a useful guideline for green building cost-efficiency strategies. Additionally, it also served as reference data for the Vietnamese public agency to update their green regulations based on the specific characteristics of Vietnam.

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Background The complex 3-dimensional (3D) nature of anatomical abnormalities in congenital heart disease (CHD) necessitates multidisciplinary group discussions centered around the review of medical images such as magnetic resonance imaging. Currently, group viewings of medical images are constrained to 2-dimensional (2D) cross-sectional displays of 3D scans. However, 2D display methods could introduce additional challenges since they require physicians to accurately reconstruct the images mentally into 3D anatomies for diagnosis, staging, and planning of surgery or other therapies. Virtual reality (VR) software may enhance diagnosis and care of CHD via 3D visualization of medical images. Yet, present-day VR developments for medicine lack the emphasis on multiuser collaborative environments, and the effect of displays and level of immersion for diagnosing CHDs have not been studied. Objective The objective of the study was to evaluate and compare the diagnostic accuracies and preferences of various display systems, including the conventional 2D display and a novel group VR software, in group discussions of CHD. Methods A total of 22 medical trainees consisting of 1 first-year, 10 second-year, 4 third-year, and 1 fourth-year residents and 6 medical students, who volunteered for the study, were formed into groups of 4 to 5 participants. Each group discussed three diagnostic cases of CHD with varying structural complexity using conventional 2D display and group VR software. A group VR software, Cardiac Review 3D, was developed by our team using the Unity engine. By using different display hardware, VR was classified into nonimmersive and full-immersive settings. The discussion time, diagnostic accuracy score, and peer assessment were collected to capture the group and individual diagnostic performances. The diagnostic accuracies for each participant were scored by two experienced cardiologists following a predetermined answer rubric. At the end of the study, all participants were provided a survey to rank their preferences of the display systems for performing group medical discussions. Results Diagnostic accuracies were highest when groups used the full-immersive VR compared with the conventional and nonimmersive VR (χ22=9.0, P=.01) displays. Differences between the display systems were more prominent with increasing case complexity (χ22=14.1, P<.001) where full-immersive VR had accuracy scores that were 54.49% and 146.82% higher than conventional and nonimmersive VR, respectively. The diagnostic accuracies provided by the two cardiologists for each participant did not statistically differ from each other (t=–1.01, P=.31). The full-immersive VR was ranked as the most preferred display for performing group CHD discussions by 68% of the participants. Conclusions The most preferred display system among medical trainees for visualizing medical images during group diagnostic discussions is full-immersive VR, with a trend toward improved diagnostic accuracy in complex anatomical abnormalities. Immersion is a crucial feature of displays of medical images for diagnostic accuracy in collaborative discussions.

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Background/Aim: Non-structural maintenance of chromosomes condensin I complex subunit H (NCAPH) is implicated in correct chromosome condensation and segregation during mitosis. However, the functional role of NCAPH in the pathogenesis of non-small-cell lung cancer (NSCLC) remains unclear. The aim of this study was to elucidate the role of NCAPH in NSCLC cells. Materials and Methods: A549 and H1299 NSCLC cells were transfected with small-interfering RNA (siRNA) against NCAPH. Subsequently, 3-( 4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, colony-formation assay and flow cytometry analysis were performed to reveal the role of NCAPH in NSCLC cells. In addition, migration and invasion assay were also performed. Results: NCAPH knockdown inhibited cell proliferation, induced cell-cycle arrest at G 2 /M phase, and prevented colony formation, migration and invasion by NSCLC cells. Conclusion: NCAPH is involved in NSCLC progression and development, and may be a potential therapeutic target for NSCLC treatment.Condensins are large protein complexes that play a role in chromosomal assembly and segregation during mitosis and meiosis (1). There are two different types of condensin complexes in eukaryotes, condensin I and II (2). Both complexes contain the same pair of core subunits, the structural maintenance of chromosomes (SMC) proteins, SMC2 and SMC4. Condensin I and II also contain three non-SMC subunits, NCAPD2, NCAPG, and NCAPH in condensin I; and NCAPD3, NCAPG2, and NCAPH2 in condensin II (3). SMC2 and SMC4 belong to a larger family *These Authors contributed equally to this work.

The U.S. Green Building Council’s (USGBC) Leadership in Energy and Environmental Design (LEED) certification program supports sustainable construction as part of the effort to address climate change and resource depletion. It is the world’s most popular green building certification system, with more than 146,400 projects. Satisfying the LEED requirements brings many benefits to a project’s design performance and adds community value, but it does incur additional costs and challenges. This study examined the choices made by those working on the 222 LEED New Construction version 4 (LEED-NC-V4) projects that were certified between September 2014 and March 2020 to determine how the LEED project teams selected appropriate LEED goals. The results reveal interesting insights into the way project LEED goals and the credits corresponding to the target certification level were chosen, as well as the links and trade-offs between the various credit options. Based on these findings, useful suggestions are made for ways to help LEED project teams achieve their target certification levels and encourage authorities to continue to improve their local green regulations. The analysis of actual certified projects’ data makes it possible to re-evaluate the effects of newly updated requests in LEED v4 in the light of the stated goals of the USGBC.

How do thoughts arise, unfold, and change over time? Are the contents and dynamics of everyday thought rooted in conceptual associations within one’s semantic networks? To address these questions, we developed the Free Association Semantic task (FAST), whereby participants generate dynamic chains of conceptual associations in response to seed words that vary in valence. Ninety-four adults from a community sample completed the FAST task and additionally described and rated six of their most frequently occurring everyday thoughts. Text analysis and valence ratings revealed similarities in thematic and affective content between FAST concept chains and recurrent autobiographical thoughts. Dynamic analyses revealed that individuals higher in rumination were more strongly attracted to negative conceptual spaces and more likely to remain there longer. Overall, these findings provide quantitative evidence that conceptual associations may act as a semantic scaffold for more complex everyday thoughts, and that more negative and less dynamic conceptual associations in ruminative individuals mirror maladaptive repetitive thoughts in daily life.

Anodic alumina oxide (AAO), a self-ordered hexagonal array, has various applications in nanofabrication such as the fabrication of nanotemplates and other nanostructures. In order to obtain highly ordered porous alumina membranes, a two-step anodization or prepatterning of aluminum are mainly conducted with straight electric field. Electric field is the main driving force for pore growth during anodization. However, impurities in aluminum can disturb the direction of the electric field. To confirm this, we anodized two different aluminum foil samples with high purity (99.999%) and relatively low purity (99.8%), and compared the differences in the surface morphologies of the respective aluminum oxide membranes produced in different electric fields. Branched pores observed in porous alumina surface which was anodized in low-purity aluminum and the size; dimensions of the pores were found to be usually smaller than those obtained from high-purity aluminum. Moreover, anodization at high voltage proceeds to a significant level of conversion because of the high speed of the directional electric field. Consequently, anodic alumina membrane of a specific morphology, i.e., meshed pore, was produced.