Ethnobotanical field surveys were carried out in the Tanawal area of the Lesser Himalayan Region, Khyber Pakhtunkhawa, Province from April 2016 to October 2017. The area is located between 34.36 (34° 21’ 30 N) latitude and 73.07 (73° 4’ 0 E) longitude with an average elevation of 1374 meters above sea level. Ethnomedicinal data were collected through Participatory Rural Appraisal (PRA), and participants were selected through the snow-boll technique. Semi-structured, in-depth and open-ended interviews were conducted. The data were quantitatively evaluated using ethnomedicinal indices i.e. Relative frequency of citation (RFCs), Fidelity level (FL), and Use Value (UV). The ethnobotanical data were also comparatively analyzed through the Jaccard Index (JI). The study yielded 66 medicinal plants in 62 genera and 43 families. Asteraceae and Solanaceae were the most important families with five medicinal taxa each. Regarding medicinal plant part utilization, leaves (43.28%) were used predominantly, followed by whole plant (14.92%) and fruits (14.92%). Decoction was the main drug formulation applied to 21 species (31.15%) and the oral route was most common (56.1%) while 31.2% of medicinal plants were used for both oral and topical applications. Fifty health disorders were recorded and grouped in 15 categories. Maximum species were used to treat gastrointestinal disorders i.e. 13 species, dermal problems (12 species), and respiratory tract ailments (9). The calculated RFCs ranged between 81 to 31. The most important medicinal plants were Acacia modesta, Citrullus vulgaris, Tamarindus indica, and Momordica charantia with an RGFC of 81 each. The UV ranged between 0.58 and 3.6. Medicinal taxa with the highest UV were Dioscorea deltoidea (3.6), Withania coagulans (3.3), Momordica charantia (3.5), Silybum marianum and Pyrus pashia (3.2). FL values showed that 28 (41.79%) species had a FL value below 50 (74.62%) while 39 (58.20%) had higher FL values. Momordica charantia, Tamarindus indica, Acacia modesta and Citrullus vulgaris were 95.2 each. The Jaccard Index (JI) values ranged from16.77 to 0.98. The current study also reported 16 medicinal plants, commonly used around the globe, have been rarely documented for their medicinal values in the local ethnomedicinal literature i.e. Althaea officinalis, Plantanus orientalis, Jasminum sombac, Maytenus royleana, Cucurbita maxima, Phyllanthus emblica, Citrullus vulgaris. Polygonatum verticilliatum, Caseria tomentosa, Cistanche tubulosa, Bambusa arundinacea, Schinus molle, Tamarindus indica, Pongamia pinnata, Citrus limon and Catharanthus roseus. However, 48 medicinal plants had been reported in the literature but the current study reported their novel medicinal uses. Important taxa should be established in botanical gardens for in-situ conservation, chemical investigation and sustainable utilization. It would also be effective to improve the livelihoods of the local population.

Background Menstruation is a natural physiological phenomenon, yet considered a stigmatized subject, particularly in low- and middle-income countries like Pakistan. It is seldom discussed openly, leading to flow of incorrect and incomplete knowledge. The resultant unhealthy practices not only affect the health of the menstruator but can also contribute to considerable psychosocial stress. Menstrual hygiene management (MHM) is an important facet, which is associated with a variety of practices and beliefs in different parts of the world, some of which may not be correct. Identifying these poor methods is necessary in order to rectify them. Hence, our study aimed at determining the level of knowledge, beliefs, and practices pertaining to menstruation in the general female populace of Karachi. Healthcare workers have a potential role in the dissemination of authentic knowledge and practices. Therefore, we assessed and compared the accuracy and reliability of the aforementioned parameters in them and the need for an educational intervention. Methods A descriptive, cross-sectional study was conducted on females visiting the Gynecologic and Obstetrics Outpatient Department (OPD), and healthcare workers employed at Dr. Ruth K. M. Pfau Civil Hospital Karachi and Dow University Hospital Ojha. Using non-probability convenience sampling, a self-structured questionnaire was used to collect data from 353 respondents over a duration of three months from October 2019 to January 2020. Data was tabulated in Statistical Package for the Social Sciences (SPSS) version 24.0 (IBM Corp., Armonk, NY, US). In accordance with the objectives of the study, descriptive analysis was performed, and data was presented in the form of frequencies and percentages. Results Of the 353 participants, 176 were from the general population and 177 were healthcare workers. At menarche, only 28.4% of the general population and 29.4% of healthcare workers had an idea of menses and proper placement of absorbent. Significantly lower number of females from the general population were found to be aware of tampons and menstrual cups (15.9% and 11.4% respectively) as compared to healthcare workers. For both groups, the source of knowledge was mostly their mother. The study showed that 77.8% of the general population and 66.1% of healthcare workers avoided bathing on certain days during menses, with the most common reason being that "it causes irregular flow". As compared to healthcare workers, a significantly higher number of women from the general population had restrictions of activity (53.4%) and avoided washing of groin area during menstruation (31.2%). Majority of women from the general population mentioned that they were scared when they menstruated for the first time. The most common absorbent used by respondents was pads, followed by cloth. The data showed 64.2% of females from the general population and 28.8% of healthcare workers abstained from eating certain foods. Seeking treatment for gynec...

Energy is a challenging and emerging problem in the world. Most South Asian countries have limited means but they cannot utilize a major part of their resources due to the high cost of exploration. However, few countries in this region have sufficient capacity and abundant energy resources to overcome the issues related to energy, but due to several reasons, they are not going to play an effective role in this field. As we know South Asian economies have limited resources and facing energy crises due to these reasons, we conduct research on this region as well. The aim of this study is to examine the relationship between economic growth (GDP), financial development (FD), and energy consumption (ENC) for South Asian countries for the period 1991-2020. For the empirical purpose, panel co-integration approaches are applied. However, the Pooled Mean Group (PMG) long-run result shows that the impact of financial development (FD) and economic growth (GDP) on energy consumption (ENC) is positive and significant. Based on the Vector Error Correction Methodology (VECM) Granger causality results, Conservation Hypothesis holds between the economic growth (GDP) and energy consumption (ENC) in the South Asian Region both in the short-run as well as in the long run. Moreover, the results also indicate that two-way causality exists between financial development (FD) and energy consumption.

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Objectives: To quantify the depiction of violence and vulgarity in television programmes for children, and to assess the perception and practices of parents and children about television programmes meant for children. Methods:  We conducted this mixed-methods cross-sectional study in Karachi, Pakistan in the months of August-September 2018, after approval from the ethics review board of Dow University of Health Sciences, Karachi. First, a content analysis of over 102 hours of various television programmes meant for children was performed in the light of the guidelines set out by the World Health Organisation, the United States Federal Communication Commission and the Pakistan Electronic Media Regulatory Authority. Seven trained researchers sampled the children prime time throughout a week, including the weekends, using a structured tally sheet. Subsequently, interviews were conducted with dyad of parent-children from the employees’ list of a public-sector university. A questionnaire was also administered to assess the practices and perceptions of the parents-children dyad about the programmes.  Data was analysed using SPSS 24. Results: Of the 173 subjects, 84(48.6%) were parents and 89(51.4%) were children. The mean age of the children was 89 children 9.8±3.7 years. Content analysis comprised 6130 minutes, of which 5442(88.8%) had depictions of violence and vulgarity. Depiction of violence and vulgarity was prevalent on television channels that were watched the most, but there was no significant difference in this regard (p=0.238). Of the parents, 68(81%) expressed concern over the effect of screen time and content on the mental health of their children.

Objective: Compare the analgesic effects of Gabapentin and Paracetamol post-operatively in patients with hand injury. Methods: This double blind, randomized control trial was conducted at the Department of Plastic Surgery, Dow University of Health Sciences Karachi; during March to August 2019. Fifty participants with hand injury and age ranged 18-60 were enrolled through consecutive sampling; while patients with multiple traumas, psychiatric illnesses, epileptic and pregnant were excluded. Informed written consent was obtained before enrollment of participants. Participants were randomly divided into two groups. Gabapentin (600 mg) and Paracetamol (1000 mg) were provided through anonymous packaging. Pain intensity was assessed using Visual Analogue Scale (VAS) along with self-designed questionnaire which was filled twice post-operatively (first at the time of drug intake once orally allowed and 6 hours later). Computer software SPSS 22 was used for analysis and comparison of results. Results: The analgesic effects of both the groups were analyzed using paired ‘t’ test which revealed statistically significant value i.e. <0.001 for each group. Though; the correlation coefficient was slightly more promising towards Paracetamol group (0.873 and 0.743 for Paracetamol and Gabapentin respectively). While in Gabapentin group there were more change of peaks were observed. Clinically more side effects were found in Gabapentin group. Conclusion: Both the drugs were found to be effective in pain management but Paracetamol had better pain control with relatively less side-effects. Key words: Pain, Hand injury, Gabapentin, Paracetamol. Continuous...