Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. Consequence of Toxocara administration appeared attenuated in animals receiving both agents. Parasite larvae were found in the central nervous system in all infected mice.
When given the opportunity to control illumination, rats with septal lesions changed illumination conditions more often, but spent less total time in the light, than control animals. Therefore, compared with control rats, animals with septal lesions displayed both a greater preference for stimulus change and enhanced aversion for the illumination level used. A finding that such alterations in reactivity to light were maintained for 14 days was interpreted as being analogous to the effects of septal lesions on consumption of palatable and unpalatable fluids.
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