Paragangliomas (PGs) are exceptionally rare tumors. Only 24 cases have previously been reported. Both preoperative and postoperative differential diagnosis is very difficult. Due to interesting nature in diagnosis and differential diagnosis, we describe the case 58-year-old euthyroid woman with a thyroid PG. The patient had presented with euthyroid multinodular goiter to a secondary hospital. The patient was treated with right lobectomy, isthmectomy, and left partial lobectomy without any imaging procedures. No complication had been developed during and following the operation. Initial pathological examination suggested medullar thyroid carcinoma (MTC) in a nodule of 4.5 cm in diameter on right thyroid lobe and a nodule of 2.5 cm in diameter on the left thyroid lobe without amyloid stroma and referred to our third-stage hospital. Repeated pathological examination involving immunohistochemistry revealed that the tumor was stained positively to neuron-specific enolase, chromogranin A, synaptophysin, and S-100 protein. No immunoreactivity was detected against thyroglobulin, calcitonin, parathormone, carcino-embryonic antigen, thyroid transcription factor-1, and cytokeratin. A diagnosis of thyroid PG was finally made. Laboratory analyses and imaging procedures excluded any neck or extracervical tissues metastasis or multiple endocrine neoplasia. In conclusion, thyroid PG is an elusive tumor. We present this interesting nature thyroid PG case to highlight importance of careful evaluation of clinical and pathological findings to correctly identify paragangliomas which anatomically mimic MTCs. This report is the first case of thyroid PG presenting with multinodular goiter in the literature.

ÖzetMorfea lezyonları üzerinde bül gelişimi nadiren bildirilmektedir. Bu olguların çoğu morfeanın nadir bir klinik tipi olan büllöz morfea olarak isimlendirilirken, daha az sayıdaki olgu ise büllöz liken skleroatrofikans olarak tanımlanmıştır. Bu yazıda, genç bir kadın hastada fleksural yerleşimde plak tip morfea lezyonu üzerinde gelişen, histolojisi liken skleroatrofikansla uyumlu büllöz lezyon tanımlanarak, bu ilginç birliktelik vurgulanmaktadır. AbstractBullae occuring on the top of morphea is rarely reported. While most of these cases are named as bullous morphea, a rare clinical type of morphea, a few cases are described as bullous lichen sclerosus et atrophicus. In this report, the interesting coexistence of these two diseases is underlined by describing a bullous lesion with compatible histology with lichen sclerosus et atrophicus on top of flexural morphea en plaque in a young female patient. (Turk J Dermatol 2011; 5: 61-4)

Mesenteric cysts are rare lesions and they are usually asymptomatic. Acute abdomen caused by infection of cyst is a very rare complication. We present a child with mesenteric cyst who presented acute abdomen and was treated with total cystectomy. Although mesenteric cysts are usually asymptomatic, they may cause serious complications. So, even if they are asymptomatic and diagnosed incidentally, these cysts should be closely monitored and surgical treatment should be considered for large cysts.

Mesanenin sarkomatoid karsinomu (SK) malign epitelyal ve sarkomatöz komponentler içeren nadir bir tümördür ve tüm invaziv mesane tümörlerinin %3'ünü oluşturur. Literatürde şimdiye kadar çok az miktarda osteosarkom komponentli karsinosarkom bildirilmiştir. Olgumuz 83 yaşında erkek hasta makroskopik hematüri, dizüri, pelvik ağrı şikayeti ile üroloji polikliniğine başvurmuştur. Histopatolojik çalışmada osteosarkom komponent %99, epitelyal komponent %1 oranında olan karsinosarkom olarak değerlendirilmiş ve immünohistokimyasal çalışmalarla teyid edilmiştir. Bu bulgularla olguya sarkomatoid karsinom (osteosarkom komponenti baskın) tanısı verilmiştir. SK'lar tanı sırasında sıklıkla ileri evre tümörlerdir ve agresif seyir gösterirler. Patologların mesanenin bifazik tümörlerinin ayrıcı tanısında sarkomatoid karsinomu dikkate almaları doğru ve hızlı tanı için önemlidir.

No abstract