SUMMARYHiccups can be defined as the sudden, uncontrolled contractions of the diaphragm, followed by immediate inspiration and closure of the glottis over the trachea. Various etiologies are responsible for this reflex action such as instrumentations, gastrointestinal, cardiovascular, toxic-metabolic factors, and drugs. Most common drugs that may trigger hiccups are opioids, barbiturates, some antibiotics, chemotherapeutic agents, and steroids. Since steroids are one of the most common drugs in neurology practice, we here presented a patient with relapsing-remitting multiple sclerosis that experienced persistent hiccups after intravenous methyl-prednisolone treatment, to emphasize the side-effect of the drug. Keywords: Hiccups, intravenous methyl-prednisolone, side effect ÖZET Hıçkırık, trakenin üzerinden glottisin kapanması ve ani inspirasyon ile takip edilen, diyaframın ani ve kontrol edilemeyen kasılmaları olarak tanımlanabilir. Bu refleks eylemden enstrümentasyon, gastrointestinal, kardiyovasküler, toksik-metabolik faktörler ve ilaçlar gibi çeşitli etiyolojiler sorumludur. Hıçkırığı sıklıkla tetikleyen ilaçlar opiatlar, barbitüratlar, bazı antibiyotikler, kemoterapötik ajanlar ve steroidlerdir. Steroidler nöroloji pratiğinde en sık kullanılan ilaçlardan biri olduğundan, intravenöz metilprednizolon sonrası inatçı hıçkırık ortaya çıkan, atak ve iyileşmelerle giden bir multiple skleroz hastasını, ilacın yan etkisini vurgulamak amacıyla sunduk. Anahtar sözcükler: Hıçkırık, intravenöz metilprednizolon, yan etki CMJ Case Report
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