BACKGROUNDGestational gigantomastia is a very rare condition and only about 100 cases have been reported in the literature. This is the fi rst case of gigantomastia in pregnancy in our collective experience and is signifi cant because to the best of our knowledge, few cases of postpartum complete spontaneous resolution have been reported. The breasts are of vital importance to the newborn child, particularly in developing countries where breast feeding is common. Breast feeding confers numerous advantages on the infant including reduced mortality rate and improved neurological development. Physiological enlargement of the breasts occurs at puberty and during pregnancy, when it starts very early and is sustained until delivery. The factors controlling breast growth are complex and not completely understood, although oestrogens, progesterones, prolactin, growth hormone and adrenal steroids are all known to play a role. Sometimes this process goes wrong resulting in an excessively large and painful breast called gestational gigantomastia (gravidic gigantomastia, mammary hyperplasia of pregnancy) or virginal hyperplasia when it occurs at puberty. This rare but important condition of the breast not only interferes with breast feeding but may cause severe maternal morbidity and even mortality.
Introduction Trace element selenium, an antioxidant, and peroxynitrite scavenger when incorporated into selenoproteins and enzymes reduce oxidative stress which is implicated in the aetiopathogenesis of pre-eclampsia. A paucity of information exists on the serum selenium levels among pre-eclamptic pregnant women in Nigeria, hence the need for this study. Objective To compare mean serum selenium levels and prevalence of selenium deficiency in preeclamptic pregnant women and their normotensive pregnant controls. Materials and methods A comparative case-control study was carried out at the Department of Obstetrics and Gynaecology, Federal Medical Centre, Owerri, Imo state. Fifty-eight preeclamptic and equal normotensive pregnant controls were matched for age groups, gestational age groups, parity groups, and socioeconomic status had their serum samples analyzed for selenium level using atomic absorption spectrophotometer (ASS). Data analysis was done using the statistical package for social sciences (SPSS) version 20.0. P-value of < 0.05 was considered to be statistically significant. Result Mean serum selenium levels of the preeclamptic women(0.67±0.27μmol/l) was significantly (p<0.001) lower than that of the normotensive controls(1.20±0.46μmol/l). Selenium
Pregnant women (110) with successfully repaired vesicovaginal fistula, supervised at the Ahmadu Bello University Teaching Hospital in Zaria, Nigeria, formed the study population. The obstetric complications, mode of delivery and fetal outcome are reviewed. The obstetric complications and fetal outcome were compared with a matched hospital control group. There was a higher complication rate among the women with vesicovaginal fistulae, and the commonest complication was urinary tract infection. Perinatal mortality rate was 17.2% in the cases compared to 10.2% in the controls.
Two hundred and sixty-five abdominal hysterectomies performed in Ahmadu Bello University Teaching Hospital, Zaria (ABUTHZ) Nigeria form the basis of this study. The commonest indication for operation was fibroids with or without chronic pelvic inflammatory disease. The low incidence of dysfunctional uterine bleeding and endometriosis and the high incidence of trophoblastic disease were noted. The mortality rate was 0.82%. Compared to other series the morbidity rate was high and this was attributed to advanced pathology on presentation and the poor nutritional status of most of the patients.
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