Nasolabial cyst (NC) or Klestadt's cyst is a relatively rare soft tissue developmental cyst occurring in the nasolabial fold, accounting for approximately 0.7% of all non-odontogenic cysts. [1][2][3] The pathogenesis of NC remains unknown, but has been attributed to epithelial remnants retained in the nasolacrimal duct extending between the lateral nasal process and maxillary prominence. [3][4][5][6] Clinically, NC presents as an asymptomatic soft swelling in the upper labial mucosa in the area of the nasolabial fold, which may cause facial asymmetry. [1][2][3][4][5][6] Pain may be experienced by patients with secondary infection due to nasal obstruction induced by the cyst. 4,5 The condition has a predilection for females, and most patients are in the fourth to fifth decades of life. NC usually appears as a solitary lesion but 10% of cases may occur bilaterally. 7 Panoramic and intraoral radiographs usually do not reveal
Immunization is the ultimate objective to ensure safe return, for schools and jobs to be open. Fortunately, the government of Saudi Arabia had announced that Clinical trials for SARS-CoV-2 will start in August 2020. There is need to evaluate immune response among vaccinated individuals and recovered patients. The market is full of different commercial tests promoted for the health care providers. An accurate selection of tests is crucial specially that are approved by international authorities the FDA-CDC. By August 2020, forty-seven serology tests were authorized by the FDA-CDC under the -EAU emergency. The accuracy and reliability of the serological tests is reflected by the sensitivity and specificity of the test. However, serological testing has an inherent problem of false positive and false negative that are associated with tests. Therefore, the sensitivity and specificity values are not enough indicators for the interpretation of the results specially in variation of the prevalence rate. The positive predictive value (PPV)was calculated from sensitivity and specificity of 47 tests at different prevalence rates to show its effect on the interpretation of results at different populations. In conclusion, it is time to use serological testing for the public to return to normal life. Selecting the proper serological kit depends heavily on the specificity, more than the sensitivity, of the test and the prevalence of the disease among the group tested. In lower prevalence population use two kits to increase the PPV and reliability of the results.
Objetivo: O objetivo deste estudo foi relatar dois casos de pacientes do sexo feminino com diagnóstico de síndrome de Sturge-Weber (SSW), suas principais manifestações clínicas orais e maxilofaciais e tratamento odontológico. Relato de caso: Caso 1. Paciente do sexo feminino, 30 anos, encaminhada à Clínica de Estomatologia da Universidade Estadual do Rio de Janeiro para avaliação de lesão avermelhada difusa no rosto e na boca. Durante o exame clínico, foram detectadas manchas de vinho do porto (MVP) no lado direito da face e descoloração intraoral sugestiva de SSW. Como a paciente não referia sintomas, foi encaminhada a uma equipe de neurologia para investigar alterações no sistema nervoso central (SNC). Caso 2. Uma mulher de 19 anos foi encaminhada para avaliação de um sangramento gengival com duração de 5 meses na mucosa alveolar mandibular e maxilar direita. O exame extraoral mostrou a presença de MVP no lado direito do rosto. Ao exame intraoral, a hiperplasia gengival causou má oclusão, deposição de placa e sangramento grave. O diagnóstico de SSW foi estabelecido devido a esses achados. A paciente foi encaminhada para tratamento periodontal. Conclusão: Dessa forma, é essencial que o dentista tenha conhecimento das manifestações clínicas dessa síndrome, a fim de realizar seu diagnóstico e propor o tratamento correto
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