The recognition of an enteropathy caused by olmesartan is recent. It was first described in 2012 by the Mayo Clinic, which presented 22 clinical cases. Olmesartan is a highly prescribed drug and the differential diagnosis of a sprue-like enteropathy is very wide, so it is important to be aware of this pathology.We report a case of a 67-years-old man, with arterial hypertension under treatment with olmesartan, with a 4-months history of diarrhea and weight lost. He was admitted three times in our Department during this period of time. An initial diagnosis was made of lymphocytic colitis but he did not respond to treatment with corticosteroids. There was a high suspicion of celiac disease, so the patient started a gluten-free diet but still there were no symptomatic changes. The patient underwent several blood and imaging tests which were negative. Due to the suspicion of an enteropathy caused by drugs, olmesartan was stopped and the patient showed a significant improvement of his symptoms.The exact pathophysiology of this entity remains to be elucidated. It may affect all gastrointestinal tract and mimic a refractory celiac disease as well as a lymphocytic colitis due to similar symptoms and histology. It is expected more cases like this in the future due to high use of olmesartan in current clinical practice.So, it is important to all gastroenterologists to be aware of this pathology and take it into consideration when putting together a differential diagnosis.

Influência de dureza e pH na capacidade adsortiva de diuron em carvão ativado Influence of hardness and pH on adsorption capacity of diuron on activated carbonResumo A capacidade adsortiva do diuron em CAG de babaçu foi determinada experimentalmente em função do tempo de contato (0,5 h a 4,0 h), da dureza total (< 1 a 500 mgCaCO3.L -1 ) e do pH (6,0 a 9,0). Os resultados obtidos foram representados na forma de isotermas de adsorção segundo os modelos de Henry, Freundlich e Langmuir; dentre estes, a isoterma de Henry forneceu melhores ajustes. A constante de Henry tendeu a crescer em relação à dureza para pH de 6,0, enquanto que decresceu para os pH de 7,0 e 9,0, ou seja, a mudança de meio ácido para neutro ou básico fez com que as influências da dureza total em Cs e K se invertessem. Foi proposta uma correlação parametrizada na relação entre dureza total e pH para descrever esse comportamento e prever a constante de Henry com suficiente exatidão e, consequentemente, a capacidade adsortiva para diferentes condições, observados os limites de validade. Palavras-chave: Carvão Ativado Granular. Diuron. Dureza Total. Isotermas de Adsorção. Henry, Freundlich and Langmuir models, among Abstract The adsorptive capacity of diuron on granular activated carbon (GAC) was experimentally determined as a function of contact time (0.5 h to 4.0 h), total hardness (<1 to 500 mgCO3.L -1 ) and pH (6.0 to 9.0). The results were represented as adsorption isotherms according to

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