BACKGROUNDSjögren's syndrome is a rare disease, of systemic presentation, which can occur in a primary or secondary form, with a prevalence between 0.05 to 0.4% of the general population. Its association with distal renal tubular acidosis (type I) is well documented in the literature, and may occur in 5 to 25% of patients with this diagnosis.
OBJECTIVES: To report the case of a child with atipical Kawasaki disease associated with cholestatic syndrome. Kawasaki disease is an inflammatory syndrome that affects small and medium-sized vases, which cause is unknown. The diagnostic is clinical and based in classic criterions, which are commonly reported symptoms, does not including cholestatic jaundice nor hepatomegaly because they are un-usual findings. CASE REPORT: 6-year-old female presented persistent high fever, rash and gastrointes-tinal symptoms. She developed with conjunctival injection, strawberry tongue, and cracked lips, with-out improvement of the fever after the empiric antibiotic treatment. In elapsing of the disease, the rash got improvement and appeared cholestatic syndrome and classic symptoms of the disease of complete Kawasaki (unilateral cervical lymphadenopaty, conjunctival injection, and hand desquama-tion), that it made possible her diagnosis and treatment, with improvement of cholestatic syndrome, without aneurysm appearance. CONCLUSIONS: This paper shows the importance of including Kawasaki disease as differential diagnosis in cases of jaundice feverish syndromes, allowing their treatment in skilled time end prevent complications.
Diversos estudos têm demonstrado o efeito protetor do peso corporal sobre o risco de osteoporose (OP) e de fraturas por baixo impacto (Fx). No entanto, mais recentemente, tem sido verificada maior taxa de fraturas por fragilidade óssea, especialmente dos membros inferiores, em indivíduos com sobrepeso e obesidade.
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