Background The potential benefits of utilizing rapid influenza diagnostic tests (RIDT) in urgent care facilities on clinical care and prescribing practices are understudied. We compared antiviral and antibiotic prescribing, imaging, and laboratory ordering in clinical encounters with and without RIDT results. Methods Our study compared patients with acute respiratory infection (ARI) symptoms who received an RIDT and patients who did not at two urgent care facilities. Primary analysis using one-to-one exact matching resulted in 1145 matched pairs to which McNemar’s 2x2 tests were used to assess association between the likelihood of prescribing, imaging or laboratory ordering, and RIDT use. Secondary analysis compared the same outcomes using logistic regression among the RIDT-tested population between participants who tested negative (RIDT(-)) and positive (RIDT(+)). Results Primary analysis identified that compared to patients without RIDT testing, RIDT(+) patients were more likely to be prescribed antivirals (OR:10.23; 95% CI:5.78-19.72) and less likely to be prescribed antibiotics (OR:0.15; 95% CI:0.08-0.27). Comparing all RIDT-tested participants to all non-RIDT-tested participants, RIDT use increased antiviral prescribing odds (OR:3.07; 95% CI:2.25-4.26) and reduced antibiotic prescribing odds (OR:0.52; 95% CI:0.43-0.63). The secondary analysis identified an increased odds of prescribing antivirals (OR:28.21; 95% CI:18.15-43.86; P <0.0001) and a decreased odds of prescribing antibiotics (OR:0.20; 95% CI:0.13-0.30; P <0.0001) for RIDT(+) participants compared to RIDT(-). Conclusions Utilization of RIDTs in patients presenting to urgent care with ARI symptoms influences clinician diagnostic and treatment decision-making, which could lead to improved patient outcomes, population-level reductions in influenza burden, and a decreased threat of antibiotic resistance.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.