Unilateral maxillary sinus opacification is a relatively common finding. Early identification of inverting papillomas and mucoceles may avoid delay in surgical intervention, whereas acute/chronic rhinosinusitis and nasal polyposis can initially be managed medically. Careful history, endoscopic examination, and radiographic studies can often determine the responsible disease process.
Nasal endoscopy findings do not correlate with symptom scores in patients undergoing endoscopic sinus surgery for chronic rhinosinusitis. Nasal endoscopy findings correlated with CT grade in patients without asthma, but no such correlation was found in patients with asthma.
In this prospective and randomized study, no significant differences were noted between the groups receiving either immediate release or 2 weeks of mandibular-maxillary fixation. The findings support the treatment of selective mandible fractures with 2.0-mm miniplates and immediate mobilization.
Prior studies have shown that macrophages are recruited to sites of injury or infection in the sensory organs of the inner ear, but the effects of macrophages and their cytokine secretory products on the sensory structures of the ear are not known. In the present study, cultures of dissociated statoacoustic neurons were incubated with selected macrophage secretary products and the numbers of surviving neurons after 48 h in vitro were quantified. Results indicate that two macrophage secretary products, interleukin 1 and fibroblast growth factor 2, can enhance the survival of statoacoustic neurons, while another cytokine, tumour necrosis factor-alpha can diminish the survival of those neurons. Also, numerous macrophages were present in both cytokine-treated and control cultures. The findings suggest that macrophages may influence the survival of the sensory neurons of the inner ear.
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