Interactions of nanoparticles with biological matter—both somatically and in nature—draw scientists’ attention. Nanoparticulate systems are believed to be our saviors, acting as versatile drug delivery vehicles. However, they can also cause life-threatening bodily damage. One of the most important properties of nanocrystalline cerium dioxide is its antioxidant activity, which decreases the abundance of reactive oxygen species during inflammation. In this paper, we report on synergistic effects of inorganic cerium oxide (IV) nanoparticles conjugated with the antioxidative enzymes superoxide dismutase and catalase on scavenging oxygen and nitrogen radicals.
Infrared thermography (IRT), a non-invasive temperature measurement technique has been investigated and developed for use with cyclic high temperature loading. The technique utilises an infrared thermography camera (IRTC) and Rolls-Royce HE23 black thermal paint (TP). The TP is applied to a test piece surface to provide a stable emissivity value and accurate temperature measurement for the duration of thermal cycling. Spot welded type N thermocouples (NTCs) are utilised for accuracy validation of the IRTC technique for both temperature monitoring and temperature control. An evaluation of the technique has been employed upon diverse test specimen geometries and alloy compositions at temperatures between 100 and 700°C. Unfavourable effects during cyclic temperature measurement such as thermocouple shadowing are also highlighted and quantified. In combination with HE23 TP, IRTC control and measurement has proven accurate to within ±2°C NTCs, a validated cyclic high temperature measurement technique.
The pharmaceutical industry spends billions annually on marketing to physicians (over $4.3 billion in 2014). The industry as a whole has a lot of experience in determining what to say to physicians, but it is less confident when it comes to how to say it—sometimes leading to advertising that does not engage, thereby costing sales. In an effort to define a set of rule‐based guidelines for effective pharma branding, the study adapts the primary Jungian archetypes to develop the first collection of archetypal tones of voice for healthcare products. The study here demonstrates, via a series of fuzzy‐set qualitative comparative analyses that well executed ads following an archetype consistently connect with physician audiences, while nonarchetypal healthcare ads demonstrate an inconsistent performance. Such an analysis would traditionally take the form of null hypothesis significance testing (NHST), but NHST provides substantially less insights than algorithm modeling and the use of fuzzy‐set qualitative comparative analysis as this study describes.
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