IntroductionThis rapid review identifies and summarizes the effectiveness of preventative telemental health interventions. It investigates studies conducted between 2010 and 2016 that improve mood and anxiety with long-term follow-up.MethodsA literature search of three major databases was performed by four reviewers. After citation tracing, 3604 studies were discovered, and twenty of these met the inclusion criteria. Data from the papers were abstracted, assessed for quality, and effect sizes were calculated.ResultsSalient information was discussed using the Behavioural Vaccine Model of mental illness prevention. This included key concepts such as efficacy, duration of benefits, sociocultural relevance, professional guidance, peer-to-peer support, adherence, delivery and safety.ConclusionThis review suggests there are clear prolonged benefits to using technology in youth mental illness prevention. Although this is a rapidly growing area of investigation in countries around the globe, there is still a dearth of research with long-term follow-up. Future studies should aim to boost engagement by increasing motivational guidance in order to recruit at-risk youth of all demographics into these promising intervention programs.
The history and the clinical and necropsy findings are presented of a patient who died from Aspergillus fumigatus pyaemia occurring as an opportunistic infection complicating a dissecting aortic aneurysm. The diagnosis was made (and treatment instituted) during life: it rested upon repeated isolation of the organism from tracheal aspirations, a positive blood culture and positive serum precipitin reactions to A. fumigatus. Debilitating disease along with large doses of antibiotics and corticosteroids provided the conditions necessary for the normally saphrophytic fungi to become pathogenic. As the therapy for aspergillosis is still ineffective, the danger of prescribing large doses of antibiotics together with corticosteroids is stressed.Interest in the fungal diseases and especially those caused by the aspergillus species has greatly increased over the past decade. As a result, attempts to culture aspergilli are being made more frequently and the advent of skin and precipitin tests has enabled the distinction to be made between contamination and infection. Even so it is extremely rare for the diagnosis of disseminated aspergillosis to be made during life (Caplan, Frisch, Houghton, Climo, and Natsios, 1968;Rifkind, Marchioro, Schneck, and Hill, 1967); the diagnosis is usually made by histological and cultural examination of necropsy specimens. We present a case of disseminated aspergillosis diagnosed during life and treated accordingly. The gross debility of the patient and the therapeutic barrage to which he was subjected provided the conditions for a disseminated fungal infection. CASE REPORTA 51-year-old man employed as a store-keeper in a car factory was admitted to hospital because of severe throbbing pain between the scapulae and also in the lumbar region. Thirteen years earlier the upper and middle lobes of the right lung were resected for caseating tuberculosis. For two years before admission he had been treated for severe fluctuating systemic hypertension.On examination he was in severe pain and there was some tenderness and guarding in the right hypochondrium. All the pulses were present and strong; the blood pressure was 240/100 mm. Hg. Later, on the day of admission, he developed a grey facies and profuse sweating. A leaking abdominal aortic aneurysm was diagnosed and a laparotomy was performed on the following day. At laparotomy the findings were those of a slight aneurysmal dilatation of the aorta just above the aortic bifurcation with some oedema of the adventitia. Free blood was not present in the abdomen. No surgical procedure was undertaken and the abdomen was closed. On the fourth post-operative day he complained of lumbar pain and was noted to be slightly jaundiced; serum bilirubin was 69 mg./100 ml. and the haemoglobin 13-9 g./100 ml. The blood pressure was 260/160 mm. Hg, and the temperature varied between 35 5' C. and 37 5' C. A septicaemia was suspected and after three blood cultures had been taken cephaloridine was given intravenously (blood cultures proved negative). On the sixth post-o...
Two paediatric congenital heart disease patients presented with a brief history of low-grade fever without any focal symptoms. Their clinical features and laboratory tests were unremarkable; however, their blood cultures were positive that prompted further work-up. Infective endocarditis should be considered in any paediatric congenital heart disease patient who presents with fever without any other associated clinical features.
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