We present competing risks models within a semi-Markov process framework via the semi-Markov phase-type distribution. We consider semi-Markov processes in continuous and discrete time with a finite number of transient states and a finite number of absorbing states. Each absorbing state represents a failure mode (in system reliability) or a cause of death of an individual (in survival analysis). This is an extension of the continuous-time Markov competing risks model presented in Lindqvist and Kjølen [2018]. We derive the joint distribution of the lifetime and the failure cause via the transition function of semi-Markov processes in continuous and discrete-time. Some examples are given for illustration.
It is well known that some enzymes, proteins, amino-acids between other biological molecules have more than one way to be coded in the DNA. That means, there are some biological molecules that can be identified by a set of sequences. For instance, the enzyme SmaI can be recognized by the words [Formula: see text] and [Formula: see text]. In this paper, we count the number of times that a biological sequence occurs through the DNA by any of its configurations, i.e. we provide the strong law of large numbers for a word sequence. To achieve our goal, we consider that DNA is modeled by an ergodic semi-Markov chain. We also present the Central Limit Theorem. Additionally, we compute the first hitting position of a set of words.
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