A pathway
to a range of diverse heterocycles was developed using
a nucleophilic cyclization strategy. Lactams and ene-imines are accessed
in a few steps from a common precursor, and these moieties are further
elaborated to directly provide pyrroles or pyridines with extended
conjugation. Reaction conditions are mild, and a broad range of structural
types are available within a few steps.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.