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p-aminobenzenesulfonyl urea. The therapeutic properties of this compound and some of its salts are under investigation.^-Acetaminobenzenesulfonyl Ethyl-isourea.-In a fiveliter flask provided with a mechanical stirrer was placed 600 g. of anhydrous potassium carbonate, 2 liters of acetone and 100 cc. of water. The suspension of carbonate-acetone-water was stirred and cooled in an ice-bath. To this suspension 272 g. (2.2 moles) of ethyl-isourea hydrochloride was added gradually over a period of one-half hour. With each addition some water was added until the total amount was 400 cc. The ice-bath was removed after the addition and the reaction mixture stirred at room temperature for four hours.The reaction material was then poured into five liters of water, and the crude product filtered and washed. The weight of the crude dried product was 458 g. (87% yield). It crystallized from 50% acetic acid as white needles and melted at 223-224°.

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Table VII should then be: Free Energy of Formation of the Pentanes at 298.16°K. Neopentane Isopentane «-Pentane *298» calories % in equilibrium % if no mixture neopentane -3289*320

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