Objective. To investigate the effects of arteriovenous thrombolysis combined with mechanical thrombectomy on clinical efficacy, neurological function, and the changes of nerve injury markers of acute cerebral infarct (ACI) patients. Methods. A total of 143 cases with ACI admitted to our hospital from June 2017 to June 2019 were elected as research subjects. Among them, 69 cases of patients who received treatment of arteriovenous thrombolysis were considered as group A, and 74 cases of patients who received treatment of arteriovenous thrombolysis combined with mechanical thrombectomy were considered as group B. NIHSS score, clinical efficacy, vascular recanalization, adverse reactions, hemodynamics, neurological injury indexes, duration of coma, length of hospital stay, and prognosis of patients in the two groups were compared. Results. After treatment, the NIHSS score of group A was higher than that of group B (P<0.05), the clinical efficacy of group B was better than that of group A, and the incidence of adverse reactions was lower than that of group A (P<0.05). There was no difference in vascular recanalization rate, duration of coma, and prognosis between the two groups (P>0.05). Length of hospital stay, maximum peak velocity after treatment (Vs), and mean flow rate (Vm) of group A were lower than those of group B, while vascular resistance index (RI), pulsatility index (PI), serum glutamic acid (Glu), neuron-specific enolase (NES), and S100β protein detected by enzyme-linked immunosorbent assay (ELISA) of group A were higher than those of group B (P<0.05). Conclusion. Arteriovenous thrombolysis combined with mechanical thrombectomy has a significant effect on ACI, with high safety and quick effect. In addition, it has a stronger effect on improving and protecting the neurological function of patients, which is worth promoting in clinical practice.
Objective Few researchers focused on the connection between prehypertension and carotid plaque. The current study sought to define the link between prehypertension and carotid plaque in the Japanese population. Methods Carotid artery ultrasonography was performed on each individual. Ultrasonography used to identify carotid plaque. To ensure the robustness of our findings, we used multivariable logistic regression, propensity score analysis, and an inverse probability-weighting model. Results A total of 1189 Japanese subjects were included, and the prevalence of carotid plaque was 27.2% (323/1189). Those with prehypertension had a higher prevalence of carotid plaque than those without (39.4% [196/497] vs 18.4% [127/497]). The results remained stable after adjusting for potential confounders using propensity score matching (PSM) and propensity score, inverse probability weighting, and doubly robust analysis. The ORs were 1.74–2.9, all p < 0.001. Conclusions Prehypertension was associated with carotid plaque in the outpatient Japanese adult population in this cross-sectional study.
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