Sedentary lifestyle increases the risk of hospitalization for COVID-19 independently of other factors. There is enough statistics to show that exercise prevents severe forms of COVID-19, but current recommendations do not set an upper limit for exercise intensity. The hypothesis presented in the paper states that intense exercise, through blood hypoxia, increases the expression of transmembrane angiotensin-converting enzyme 2 (tACE2) in the vascular endothelium, increasing the risk of developing serious forms of disease, especially in the untrained. On the other hand, moderate-intensity exercise increases the blood concentration of soluble angiotensin-converting enzyme 2 (ACE2) which has a protective role for SARS-CoV-2 infection and may prevent complications. The importance of this hypothesis consists in the revision of COVID-19 prophylaxis programs through physical exercises, with the possibility of administration of antioxidants to speed up the adaptation of vascular endothelial cells to exertion.

In the present work we studied gelatin nanofibers containing silver nanoparticles of 14 ± 6 nm mean diameter, prepared by electrospinning. The electrospinnable solution was obtained by dropwise adding a AgNO 3 /acetic acid solution to gelatin which had previously been dissolved in a mixture of formic acid and acetic acid. The silver metallic nanoparticles were formed due to the reducing action of the formic acid. The resulted material was characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray diffraction (XRD). Subcutaneous implants in rabbits demonstrated that the gelatin nanofibers containing silver nanoparticles were resorbed with no inflammatory reactions. An increased number of secondary hair follicles developed in tissue regions close to implants, suggesting the existence of a stimulation effect of silver nanoparticles on hair follicles.

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The role of the angiotensin-converting enzyme 2 (ACE2) receptor in SARS-CoV-2 virus infection and disease progression is complex, and the interaction with exercise is being investigated. However, the virus binds to ACE2. The paper hypothesizes that exceeding the lactic threshold during exercise would cause, through hypoxia, over expression of ACE2. Vasodilators would prevent hypoxia and implicitly this fact. To the complexity of the phenomenon is added the possibility of preventing severe forms of COVID-19 through mitochondrial biogenesis induced by exercise. As a result, the paper examines the ability of antihypertensives used in combination with exercise to treat cardiovascular disease to prevent ACE2 over expression and to stimulate mitochondrial biogenesis. Future research is needed, but it is worth mentioning that some such hypertensives have been proposed for the treatment of COVID-19.

Introduction: Since strength and endurance training has become very popular, we aimed to assess the possibility of hypoxemia determined in peripheral blood during exercise, starting from the hypothesis that a relatively large muscle mass would have a protective effect. Aim: Hypoxemia can cause serious illness and therefore we consider it useful to investigate the occurrence of this phenomenon during exercises of strength or endurance. Methods: The preliminary study was conducted on 8 subjects, both trained and untrained. With a Beurer pulse oximeter, heart rate and oxygen saturation of the capillary blood were measured before, during, and at the end of strength, or endurance or endurance combined with strength training. Results: The results have shown that hypoxemia occurs only under the conditions of high intensity training, which alternates endurance with strength exercises, simultaneously with decreasing heart rate, only in trained subjects and with relatively low muscle mass. Conclusions: The decrease in oxygen saturation in the peripheral blood occurs simultaneously with that of heart rate and it seems that large muscle mass has a protective effect on oxygen desaturation.

This article establishes the existing correlations between the anatomical location of muscle trigger points and their ability to affect joint mobility. Deeply located muscles, such as the brachialis and piriformis, do not have joint biomechanical consequences when they contain trigger points, but are more difficult to approach therapeutically, in the sense that they require the injection of anesthetics or anti-inflammatories, the maneuver being guided by ultrasound. Theoretically, patients with arthritis are more exposed to being affected by such trigger points. Cervical or temporo-mandibular biomechanical disorders are caused by trigger points in the trapezium, respectively sternocleidomestoid.

Low lumbar pain is a very common condition that can benefit from kinetotherapy, which can be combined with specific medication and cognitive therapy. Depending on the pathophysiological mechanism of production, some physiotherapy exercises or techniques can be highlighted, because they have an increased efficiency in combating this type of pain. Thus, in the case of lower lumbar pain inherent to fibromyalgia, aerobic exercises appear to be more useful, and in the case of pain that accompany a herniated disc are recommended strenght exercises and lumbar stabilization. Lower lumbar pains due to work accidents are particularly beneficial for aerobic exercise if muscular contractions are present, and those with a sacroiliac joint dysfunction as an etiology can be alleviated by Mulligan mobilizations, Mulligan tapping and ultrasound; for those caused by spinal osteoarthritis are especially useful yoga and stretching exercises. Lower lumbar pain can also be caused by ankylosing spondylitis, in which case they can be improved by gymnastics, hydrotherapy, massage, leisure activities.

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