Non-accidental injury should be suspected and excluded in any infant found to have intracranial and retinal haemorrhage of unknown aetiology. This can be a sensitive issue for both medical staV and parents. We present a case in which the underlying cause of intracranial and retinal haemorrhage was fibromuscular dysplasia. It was a diagnosis made only at postmortem examination and it illustrates the diagnostic diYculty such cases may present.
Familiar music facilitates memory retrieval in adults with Alzheimer's disease and other forms of dementia. This raises the possibility that music can be used as a rehabilitative tool to aid memory abilities more generally. However, the mechanisms behind this effect, and its generality, are unclear because of a lack of parallel work in healthy aging. In particular, exposure to familiar music enhances spontaneous recall of memories directly cued by the music, but it is unknown whether such effects extend to deliberate recall more generally — e.g., to memories not directly linked to the music being played. It is also unclear whether familiar music cues boost recall of specific episodes versus more generalized semantic memories, or whether its effects are partly driven by domain-general mechanisms (e.g., improved mood). In the current study, we will examine the effects of familiar music on deliberate recall and differentiate potential underlying mechanisms. We will expose healthy adults ages 65-80 years old (N = 75) to familiar music clips from earlier in life, unfamiliar music clips, and non-musical audio clips across three study sessions. Immediately after each clip, we will assess free recall of remote memories for pre-selected events. Those memories will then be scored for episodic and semantic details using the Autobiographical Interview. We hypothesize that familiar music may enhance recall of specific events, such that participants will recall more episodic details after exposure to familiar music than unfamiliar music or non-musical audio. We will also test a competing hypothesis that familiar music may prompt more general recollections of periods of life, and thus will increase recall of semantic details in comparison with the unfamiliar music and no-music conditions. The results of this study will advance knowledge of the mechanisms by which music affects memory, with potential implications for the use of music as a therapeutic device for declining memory.
A prospective, double masked, randomised study was performed to compare the speed of onset of peribulbar anaesthesia using pH adjusted 0.75% bupivacaine, with and without the addition of hyaluronidase. No significant difference in speed of onset occurred due to the addition of hyaluronidase. There were 7 cases of post operative ptosis in the study group, including 1 case of orbital apex syndrome and 2 cases of transient 3rd nerve palsy. This incidence of post operative ptosis using pH adjusted 0.75% bupivacaine was statistically significantly greater than in a matched control group who received a 50:50 mixture of 1% lignocaine and 0.5% bupivacaine with hyaluronidase (p < 0.05). The possible causes of this increased incidence of post operative ptosis are discussed.
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