Sublingual administration of tacrolimus is feasible and provides similar drug exposure compared with oral administration. In our study, at long-term follow-up, sublingual administration was not associated with liver transplant rejection.
Accuracy of magnetic resonance cholangiopancreatography for the diagnosis of common bile duct stones Background: Magnetic resonance cholangiopancreatography (MRCP) is a non-invasive diagnostic method for choledocholithiasis. Aim: To evaluate the results of MRCP in the diagnosis of choledocholithiasis. Patients and methods: Retrospective review of MRCP reports performed between October 2001 and December 2004. We included patients with suspected choledocholithiasis who were studied with MRCP and some other confirmatory test such as endoscopic retrograde cholangiopancreatography (ERCP), surgical common bile duct exploration or transcystic colangiography (TC). Results: One hundred and twenty five patients aged 58±20 years (70 females) were included. In 54 patients (43%) we compared the results of MRCP with the findings of surgical common bile duct exploration or TC and in 71 (57%) we did so with ERCP. MRCP suggested choledocholithiasis in 93 patients and in 32 it was negative. Eighty six (67%) patients had choledocholithiasis according to TC or ERCP, including 3 patients who had a negative MRCP. Therefore the sensibility was 97%, specificity 74% positive predictive value 89%, negative predictive value 90% and accuracy of MRCP was 90% for the diagnosis of choledocholithiasis. Conclusions: MRCP has a high accuracy for the diagnosis of choledocholithiasis (
Outcome of surgical treatment of liver metastasis from colorectal cancer 1 (1990-1997) and period 2 (1998-2007 (77% and 55%, respectively, p =0.04), without an increase in complications (35% and 34%, respectively; p =ns), but with a better five years survival (45% and 21%, respectively, p =0.04). Conclusions: Five years survival for excision of liver metastatic colorectal cancer in our center is similar to that reported abroad. During the second period there has been a trend toward more extensive resections which was associated with a better survival, without an increase in complications or mortality (Rev Méd Chile 2009; 137: 487-96).
Simplified criteria for the diagnosis of AIH have a high accuracy in our Chilean-Hispanic cohort. The female gender is strongly associated to AIH and could help in difficult cases. Further studies with a prospective design are necessary to confirm these observations.
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