Tooth cementum annulation, the microscopic method for the determination of an individual?s age, gives results that are highly correlated with the chronological age of an individual. Nevertheless, this method is still rarely used for age estimation in archaeological populations. In this study, using the tooth cementum annulation method, teeth of 21 individuals of the Djerdap anthropological series, dated to a period from the 10th to the 6th millennium BC, were analysed. The obtained data are important for overcoming some methodological issues in anthropology of the Danube Gorges, as well as with the precise age estimation of old individuals and with the assessment of age in cases where the skeletal material has been very poorly preserved. The only obstacle to the full application of the tooth cementum annulation method is the taphonomy changes of tooth cementum which were detected on several teeth in this study. [Projekat Ministarstva nauke Republike Srbije, br. 47 001: Bioarchaeology of ancient Europe - people, animals and plants in Serbian prehistory]
Background/Aim. Tuberculosis in the second decade of the 21st century is an infectious disease with the highest mortality rate. In addition, in developed countries, pneumonia is the major couse of morbidity and mortality in adults. The aim of our study was to point out the differences and similarities between symptoms, laboratory parameters and clinical indicators in patients with pulmonary tuberculosis (PTB) and patients with pneumonia in the general population and in people belonging to the high risk groups for developing tuberculosis. Methods. This prospective study included patients with PTB (n = 70) and pneumonia (n = 75) treated at the Pulmonology Department of Clinical Hospital Center in Kosovska Mitrovica. Results. PTB was more frequent in men, 30-39 years of age (OR; 6:08), mainly from rural areas (p = 0.001), and with lower levels of education (p = 0.031). Pneumonia was more frequent in women older than 60 years of age (p = 0.0012). Night sweats (p = 0.001) and weight loss (p = 0.062) were significantly more frequent in patients with PTB, while chest pain (p = 0.001) and high temperature (p = 0.036) were more common in patients with pneumonia. X-ray changes in patients with PTB were located in the upper fields (p = 0.001), or appeared to be bilateral (p = 0.004). The strongest predictor associated with an increased risk of night sweats was diagnosed PTB (OR = 30.0). The chest pain was a predictor of pneumonia, unilateral changes (OR = 4.65) in the lower lung fields (OR = 0.08). Conclusion. Night sweats, weight loss and chest X-ray abnormalities in upper fields were significant indicators of PTB. Chest pain, fever and chest X-ray abnormalities in lower fields were significant indicators of pneumonia.
Pulmonary tuberculosis in the elderly shows a specific clinical presentation in relation to younger persons. The aim of this study was to examine the influence of age and possible risk factors on pulmonary tuberculosis, clinical features of disease and lung x-ray findings. The research included 151 patients who had been treated at the Pulmonary Department of the Health Centre in Kosovska Mitrovica in the period from 2005 to 2009. Younger patients often suffer from severe forms of tuberculosis with caverns (46.9%), a significantly higher number of their sputum is positive for bacillus Kohn and they show a greater tendency towards alcoholism. A common symptom in older patients is dyspnea and radiographic changes are the most intense in the lower lung fields. The number of younger people suffering from severe forms of cavernous tuberculosis is significantly higher. Sputum findings are often negative, the caverns are found less often and lower lung fields are affected more often in the elderly.
Background/Aim. Tuberculosis (TB) is a major cause of mortality and morbidity worldwide, affecting different countries disproportionally. Effective diagnosis and treatment of TB saved an estimated 43 million lives between 2000 and 2014. The aim of our study was to show sociodemographic influences, risk factors for the morbidity and clinical characteristics of tuberculosis among residents of northern Kosovo, Serbia, between two decades at the beginning of the 21st century. Methods. A prospective study was conducted at the Department for Pulmonology of the Clinical-health Centre, Kosovska Mitrovica, included all tuberculosis patients treated during two three-year periods, between 2000?2002 and 2012?2014. In total, 134 patients with tuberculosis were treated, 91 in the first observed period and 43 in the second period. Results. In both observed periods, male patients suffered from tuberculosis more frequently. In the first observed period, younger and middle age (18?49) persons suffered from tuberculosis more frequently (p = 0.014). In relation to the place of residence, in the first reporting period there were more patients from urban areas, while in the second, there were significantly more patients from rural areas (p = 0.008). In the second observed period, TB was significantly more associated with chronic obstructive pulmonary disease (p = 0.001) and comorbidities with TB were significantly more frequent (p = 0.006). During the 2000?2002 period, there were more severe clinical forms, with severe radiological changes, bilateral parenchymal and cavernous forms (p = 0.08). Mild unilateral parenchymal lesions were more common in the last 3 years (p = 0.02). Conclusion. Social determinants, older age and comorbidities are the most important risk factors for the persistent number of patients, and therefore this target group needs attention during active approach in TB screening.
ODELJENJE PULMOLOGIJE, KLINIČKO-BOLNIČKI CENTAR KOSOVSKA MITROVICA, SRBIJA Sažetak:Cilj našeg istraživanja bio je da prikažemo sociodemografske faktore i kliničke karakteristike kod obolelih od sputum negativne i sputum pozitivne tuberkuloze pluća. Metodologija: Prospektivnom studijom obuhvatili smo sve obolele od plućne tuberkuloze (N=43) lečene na odeljenju Pulmologije Kliničko-bolničkog centra u Kosovskoj Mitrovici u periodu od 2012. do 2014. godine. Rezultati: Od sputum negativne tuberkuloze lečeno je 15 (35%) obolelih. Sputum pozitivna tuberkuloza pluća bila je značajno češća kod osoba mlađe životne dobi (p=0.05), dok su osobe koje su starije od 50 godina podjednako obolevale od sputum pozitivne ili sputum negativne tuberkuloze. U odnosu na pol, mesto stanovanja i porodični status nije bilo razlike između obolelih. Značajno više obolelih od sputum negativne tuberkuloze pluća bilo je nižeg stepena obrazovanja (p<0.001). Kašalj i iskašljavanje su podjednako bili česti. Hemoptizije su bile ćešće kod sputum pozitivne tuberkuloze pluća (p=0.08). Noćno znojenje i malaksalost bili su jednako česti kod obe grupe obolelih. Anemija je bila značajno češča kod sputum negativne tuberkuloze (p=0.037). Nije postojala značajna razlika u radiografskim promenama između sputum negativne tuberkuloze i sputum pozitivne tuberkuloze pluća. Pridružene bolesti su jednako bile zastupljene kod obe grupe obolelih, osim hronične opstruktivne bolesti pluća od koje su češće bolovali pacijenti sa sputum pozitivnom tuberkulozom. Zaključak: Sputum negativna tuberkuloza pluća je bila zastupljena kod oko jedne trećine obolelih od tuberkuloze i češće su bolovale osobe starije od 50 godina sa nižim stepenom obrazovanja. Anemija je bila izražena kod sputum negativne tuberkuloze. Hemoptizije i hronična opstruktivna bolest pluća su bili češći kod sputum pozitivne tuberkuloze. Ključne reči: sputum negativna tuberkuloza pluća, sociodemografski faktori, kliničke karakteristike Summary: The aim of our study was to show socio-demographic factors and clinical characteristics in patients with smear negative and smear positive pulmonary tuberculosis. Methodology: The prospective study included all patients with Pulmonary tuberculosis (N = 43) treated at the Pulmonology Department of the Clinical Hospital Center in Kosovska Mitrovica during the study period 2012-2014. Results: 15 (35%) patients were treated for smear negative tuberculosis. Smear positive pulmonary tuberculosis was significantly more common in younger population (p = 0.05), while people above age 50 were equally infected with both smear positive and smear negative pulmonary tuberculosis. In relation to gender, place of residence and marital status there was no difference between the patients. Significantly more patients with smear negative pulmonary tuberculosis had lower level of education (p <0.001). Cough and expectoration were equally frequent. Hemoptysis was more likely in smear positive pulmonary tuberculosis (p = 0.08). Night sweats and exhaustion were equally present in both groups ...
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