Background: Artemisia afra is an indigenous plant used in Africa. It is used in traditional medicine to treat a variety of diseases caused by bacterial infections. As a result, developing innovative therapeutic methods using natural ingredients to combat pathogenic germs is critical. Methodology: Artemisia afra leaves were extracted using maceration extraction utilizing three solvents (petroleum ether, ethanol, and dichloromethane). Fresh leaves were extracted using hydrodistillation. The agar well diffusion method was used to test the crude extract and essential oil leaves of Artemisia afra against different human pathogenic bacteria strains (E. coli, S. aureus, E. faecalis, and K. pneumonia) at different concentrations in the presence of a positive (ciprofloxacin 5.0 μg) and negative (DMSO) control. Results: Artemisia afra revealed the presence of alkaloids, flavonoids, tannins, saponins, anthraquinones, terpenoids, coumarins, phenolic quinones, cardiac glycosides, and steroids. It showed that the highest antibacterial activity given by the ethanol extract had highly inhibition zones against gram-positive and gram-negative bacteria. The essential oil extract was effective against all tested bacteria. Conclusion: Plant crude extracts and essential oils may have antibacterial properties due to the synergistic activity of two or more active secondary metabolites.
To cure ailments, the global population makes medicines from plants. Ficus palmata can be used to cure a variety of ailments. The purpose of this study was to examine the phytochemical content and antibacterial activity of methanol extract from Ficus palmata fruit and leaf crude extract. Maceration was used to make the methanol extracts, which were subsequently fractionated. The crude extracts and fractions were subjected to standard phytochemical screening assays. Phytochemical screening revealed the presence of flavonoids, alkaloids, saponins, tannins, polyphenols, anthraquinones, steroids, coumarins, and terpenoids in the crude methanol fruit extract. Phytochemical screening revealed the presence of flavonoids, alkaloids, tannins, polyphenols, anthraquinones, steroids, and terpenoids in the extract. The determination of trace metals in leaves and fruit samples using a flame atomic absorption spectrophotometer revealed that the fruits contained relatively high quantities of iron and other nutritionally essential elements, such as magnesium, calcium, and copper, whereas the leaves contain a high level of calcium, magnesium, and iron, as well as a small amount of copper.
The majority of the world population prepares medicines from plants to cure diseases. Schinus molle linens is a multipurpose plant that has been used for various remedies as constituents of traditional medicine. The aim of this study was to investigate the chemical constituents and antimicrobial activity of methanol extract and solvent fraction extracts of the stem bark of Schinus molle. Powder of Schinus molle was extracted with methanol by using the maceration method and the fractions were obtained by successive fractionation of the methanol extract with n-hexane, chloroform, ethyl acetate, and n-butanol. Preliminary phytochemical analysis of the crude methanol extract revealed the presence of flavonoids, terpenes, anthraquinones, alkaloids, tannins, phenols, and saponins. In addition to this, the antimicrobial activity of crude and solvent fraction extract was tested against S. aureus, E. faecalis, E. coli, and C. albicans at a concentration of 90.0, 180.0, and 900.0 μg/ mL. The crude methanol extract and chloroform fraction exhibited greater activity against gram-positive, gram-negative bacteria and fungi. The n-hexane and n-butanol fractions showed the least activity against most test bacteria and fungi. The study showed that it is possible to inhibit the growth of bacteria and fungi at different concentrations.
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