Recent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) system integration and measurement set-ups. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed.
Differently sulfonated polyaniline copolymers have been utilized as matrices for the entrapment of PQQ-GDH, resulting in a direct bioelectrocatalytic response together with a colour change upon addition of the substrate.
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