These results reveal that SMC is powerful in ameliorating AD-related neuropathology and cognitive deficits via modulating oxidative stress, metal homeostasis, and extracellular signal-regulated kinase (ERK) activation.
A novel one-pot Fischer indole synthesis approach has been developed by using Brønsted acidic ionic liquids as dual solvent-catalysts. Yields of 83-97 % were obtained after reaction in BMImHSO 4 at 70-110°C in 0.5-6 h, and exclusive formation of 2,3-disubstituted indoles was observed in the reaction of alkyl methyl unsymmetrical ketones. The indoles produced could be conveniently separated from the reaction
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