Limb body wall syndrome (LBW) is one of the rarest malformation complexes. It is also known by other names as « Abnormal stem of the body » « Congenital absence of the umbilical cord » and « cyllosome and Pleurosomus » [1]. This complex is a heterogeneous disease characterized by multiple severe congenital abnormalities of the fetus with exencephalon/thoraco-encephalo and/or abdominoschisis (anterior parietal malformations) and malformations of the limbs, with or without facial slits. The diagnosis remains difficult to establish in view of the clinical polymorphism the prenatal ultrasound can detect this abnormality during the first trimester. The exact etiology of this condition is still uncertain, the theory of amniotic bands of Tropin and the vascular theory (early vascular accident) of Van Allen have not succeeded in explaining all the abnormalities observed in the LBWC [2]. Karyotype study are normal and there has been no evidence of correlation with sex, age of parents or teratogenic agents. Prognosis is fatal death occurring in antenatal or early neonatal period. We are describing two cases of Limb body wall syndrome (LBW).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.