Administration of autologous invariant natural killer T (iNKT) cells was safe and well-tolerated in patients with HCC (BCLC B/C).• Expanded iNKT cells produced Th1-like responses with possible antitumor activity.• No severe adverse events were observed in any of the enrolled patients, including one patient who received 10 10 in vitro-expanded autologous iNKT cells as a single infusion.
Different MDR characteristics were exhibited in well and poorly differentiated gastric carcinomas, which may be caused by different expressed MDR associated factors in these tissues.
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