A metal-free room temperature decarboxylative cross-coupling between cinnamic acids and arylsulfonyl hydrazides has been realized for the first time for the synthesis of (E)-vinyl sulfones. The scope and versatility of the reaction has been demonstrated by the regio- and stereoselective synthesis of 22 derivatives with diverse structural features.

This protocol describes the catalytic use of diacetoxyiodobenzene (DIB) for the efficient transamidation of carboxamides with amines under mild conditions.

An efficient, fast, and green synthesis of benzimidazolo/benzothiazolo quinazolinone derivatives has been developed under solvent‐free conditions by the reaction of 2‐aminobenzimidazole/2‐aminobenzothiazole, aromatic aldehydes, and 1,3‐diketones. This method extended the application of microwave irradiation and scandium triflate combination and also tenders a lot of benefits such as excellent product yields, shorter reaction time, easy isolation of products, and environmentally benign reaction conditions.

An expedient and efficient one‐pot three‐component synthesis of 3‐substituted indoles has been developed by the reaction of indoles, active methylene compounds and aldehydes using a catalytic amount of tetrabutylammonium fluoride under solvent‐free conditions.

A practical nickel‐catalysed approach has been developed for the CS bond formation through the cross‐coupling of arylsulfonyl hydrazides and aryl boronic acids. The report employs arylsulfonyl hydrazide as an aryl thiol equivalent and offers a mild and eco‐safe synthesis of unsymmetrical thioethers in good to excellent yields in air. The scope and versatility of the method has been successfully demonstrated with 22 examples.magnified image