IntroductionAcne has long been associated with many psychiatric comorbidities.AimTo determine anxiety and depression levels, social phobia frequency, social anxiety level, subjective stress perception, anxiety sensitivity, disability, and the frequency of type D personality in patients with acne.Material and methodsIn total, 61 patients with acne aged > 16 years and 61 age, gender, and educationally matched healthy volunteers were included in the study. The patients and healthy controls were evaluated using the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 criteria for social anxiety disorder and completed the Liebowitz Social Anxiety Scale, Sheehan Disability Scale, Anxiety Sensitivity Index, Hospital Anxiety and Depression Scale, Perceived Stress Scale (PSS), and Type D Scale-14.ResultsDepression, anxiety, social anxiety, self-reported stress, anxiety sensitivity, and disability levels were significantly higher in patients with acne than in healthy controls (p < 0.05). Type D personality was more prevalent in patients with acne than in healthy controls (49% vs. 18%, p < 0.001).ConclusionsTo our knowledge, this study is the first reported in which type D personality and anxiety sensitivity, as well as social anxiety disorder according to the DSM-5 criteria, was evaluated in patients with acne compared with healthy controls. This study shows that patients with acne have higher levels of depression, anxiety, social anxiety, self-reported stress, anxiety sensitivity, and disability, and a greater prevalence of type D personality, than healthy controls. Psychiatric evaluation of patients with acne may aid the detection of mental disorders.

We enrolled 32 patients that had visited our dermatology clinic and had been diagnosed histopathologically with psoriasis, and 22 healthy subjects as the control group. The exclusion criteria for both groups were age < 18 years, diagnosis of erythrodermic or pustular psoriasis with only palmoplantar involvement, and receipt of any systemic treatment for psoriasis or phototherapy in the previous 3 months. Subjects with psoriatic arthritis, any systemic disease, receipt of treatment, or any infection in the 4 weeks before the study were also excluded. The control group was selected from subjects of similar age, sex, and body mass index (BMI) to the patient group. The type of psoriasis, disease duration, and medication history were noted for each participant. The Psoriasis Area Severity Index (PASI) was used to evaluate the severity of the disease.

Gorlin-Goltz syndrome is a rare multisystemic disease inherited in an autosomal dominant pattern. It is characterized by numerous basal cell carcinoma of the skin, jaw cysts, and skeletal anomalies such as frontal bossing, vertebral anomalies, palmoplantar pits, and falx cerebri calcification. There is a tendency to tumors including medullablastoma, fibroma, rabdomyoma, leiomyosarcoma etc.. The diagnosis is based on major and minor clinical and radiologic criteria. Early diagnosis and treatment are of utmost importance in reducing the severity of long-term sequelae of this syndrome. In this article, we present a 15-year-old boy who was admitted to our clinic with brown-black papules and plaques on his scalp and was thought to have Gorlin-Goltz syndrome. He had a history of medulloblastoma that was treated with surgical resection followed by cranial radiotherapy and unilateral retinoblastoma. We present this case, because association of Gorlin-Goltz syndrome and retinoblastoma has not been described previously in the literature and we aimed to draw attention to radiation-induced basal cell carcinomas.

Insights into chest computed tomography findings in Behcet's disease Introduction: To evaluate the spectrum and frequency of abnormal chest multidedector computed tomography (MDCT) findings in Behcet's disease(BD). Materials and Methods: Chest MDCT scans of 44 patients referred to radiology department for chest symptoms those had prior or newly established diagnosis of BD between 2009-2016 were retrospectively reviewed. Abnormal findings within pulmonary artery (PA), lungs, other large vessels, heart, mediastinum, pleura and pericardium were noted. results: Sixteen patients had one ore more computed tomography (CT) findings related to BD. PA involvement was most common (27.2%) presentation revealing thrombosis in 8 and aneurysms in 4 of 12 patients. Mean PA diameter was 29 ± 3.7 mm. Patients with PA involvement had significantly higher PA diameters than those without (p< 0.001). Hypertrophied bronchial artery seen as serpiginous vessels around hilum was a common finding (66.6%). Lung parenchyma findings was rarely isolated and usually associated with PA involvement with subpleural alveolar opacities, focal atelectasis and ill-defined nodular opacities. Cardiac filling defects were accompanying lesions in most of patients with PA aneurysms (75%). conclusion: BD is associated with a wide spectrum of simultaneous involvement of discrete anatomical sites. PA enlargement and hypertrophied bronchial artery is a clue for patients with PA involvement. Heart chambers should be checked for filling defects particularly in patients with PA aneurysms.

Demodex mites may induce inflammatory cutaneous reactions such as papulopustular rosacea and demodex folliculitis; both may lead to post inflammatory pigmentation. A 59-year-old man presented with an asymptomatic, hyperpigmented plaque on his face. Histological and clinical findings displayed Riehl-like facial pigmentation. Multiple demodex mites at the follicular infundibulum in the biopsy material were remarkable. There are limited publications about demodex-associated pigmentation. We report this case to point out that various hyperpigmentation disorders may occur simultaneously with demodex mites.

To the best of our knowledge, this is the first study to evaluate both cEMT and cIMT in BD. This study presents morphological evidence of subclinical atherosclerosis in terms of cIMT. Although there was no significant increment in cEMT, it has the potential to assess endothelial dysfunction in BD. Further studies are required to confirm this finding.

Bullous pemphigoid (BP) is a rare autoimmune blistering disorder that affects the elderly population. In this study, we retrospectively evaluated the clinical, demographic characteristics and comorbid diseases in patients with BP. Mean platelet volume (MPV), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are known to be the indicators of inflammation. We also investigated MPV, NLR, and PLR values in patients with BP and a control group. To our knowledge, there is no previous study in the literature researching NLR, PLR and MPV together in patients with BP. Method: A total of fourteen patients with BP and fourteen control subjects were included in the study. Medical reports of the patients who received clinical and histopathological diagnosis of BP between 2008 and 2018 were reviewed. MPV, NLR, and PLR values were recorded in BP patients and the control group. Results: Of the 14 patients, 9 were female and 5 male. The most frequent comorbid chronic disease was hypertension, which was detected in 7 (50%) patients. Four of the 7 patients with hypertension had coronary artery disease (28,5%) at the same time. The NLR of patients with BP was significantly higher than that of the control group (p = 0.01). There was no difference in PLR and MPV between the groups. Conclusions: The most common comorbidity in patients with BP in our study was cardiovascular diseases. More studies are needed to investigate the association between BP and cardiovascular disorders. In addition, NLR may be an inexpensive and simple parameter of inflammation in patients with BP and needs to be developed further.

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