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BACKGROUND:We aimed to evaluate the risk factors, clinical features and outcomes of surgery for traumatic wound dehiscence (TWD) following penetrating keratoplasty (PK).

Objective Clinical manifestations of Graves' ophthalmopathy (GO) are caused by the overcompression of orbital tissues within the restricted orbital bone cavity. Impaired ocular blood flow may disrupt the retinal microstructure and functions. In this study, we aimed to investigate the macular and choroidal thickness changes in GO compared with healthy subjects. Materials and Methods The study group comprised 50 adult patients with previously diagnosed Graves' disease with ophthalmopathy who were on antithyroid treatment. For the assessment of GO activity, the VISA (vision, inflammation, strabismus, and appearance) inflammatory score was used. When euthyroidism was achieved without side effects, the patients were referred to the ophthalmology clinic for spectral-domain optical coherence tomography (SD-OCT) evaluation. Results Subfoveal, mean, and temporal choroidal thicknesses were increased significantly in the study group according to the controls. The mean choroidal thickness was elevated. Conclusions This elevation is because of the intraorbital inflammation even in this nonsevere GO group. Choroidal thickness might be affected from the venous obstruction and congestion in patients with GO. The elevation of the choroidal thickness might be an early sign of venous congestion that occurs before the elevation of intraocular pressure.

Purpose:To investigate ambylopia and amblyopia risk factors of children who underwent nasolacrimal duct (NLD) irrigation and probing for congenital nasolacrimal duct obstruction (CNLDO).Materials and Methods:The medical records of patients who had undergone NLD irrigation and probing for CNLDO at an age of 3 years or younger were reviewed, and 51 of the patients were recalled between October 1 and December 31, 2011 for a detailed ophthalmic examination to determinate amblyopia or amblyopia risk factors. Amblyopia was accepted as difference in visual acuity of two or more Snellen lines between the two eyes or visual acuity of 20/30 or worse in either eye.Results:The median age of the 51 patients to whom NLD irrigation and probing were attempted for CNLDO was 23 months. CNLDO affected a total of 70 eyes. All patients were reviewed for best-corrected visual acuity, refractive errors, and strabismus at a median age of 70.5 months (range 31-95 months). Amblyopia or amblyopia risk factors were identified in 14 patients (27.5%). One child (7.15%) had only strabismus, six children (42.8%) had only amblyogenic refractive errors, two (14.3%) had a combination of two, one child (7.15%) had a family history for amblyopia, but four children (28.6%) had no amblyopia risk factors but had amblyopia.Conclusion:Amblyogenic risk factors are found higher in patients with CNLDO and patients undergoing NLD irrigation and probing in comparison to normal population. Therefore, we recommend these children to routinely undergo cycloplegic refractions and full ophthalmic examinations.

Background The aim of study was to evaluate the retinal layers and macular capillary network with OCTA in acromegaly patients, to compare with healthy population. Methods In this prospective, observational, and comparative study, 40 acromegaly patients and 40 healthy control participants were included. Serum IGF-1 levels and disease duration of all patients were noted. Macular layers and angiography scanning was performed with a Zeiss Cirrus 5000 OCTA system. Macular thickness, RNFL, and GC-IPL values were obtained. For central vessel and perfusion density, central 6 mm was obtained and was evaluated by dividing into three groups (inner, outer, full). FAZ parameters were evaluated dividing into three groups (area, perimeter, circularity index). Analysis of the data was performed with the SPSS for Windows. Results There was no significant difference between the patient group and the control group in terms of age, gender, best corrected visual acuity (BCVA), spherical equivalent (SE), intraocular pressure (IOP), and axial length (AL). The mean follow-up period after diagnosis was 11.0 ± 5.5 years. Central and mean macular thicknesses were also significantly higher in the acromegaly group (p < 0.05). Superior, inferior, and average RNFL thicknesses were also significantly thinner in the acromegaly group (p < 0.05). When OCTA parameters were compared between groups, there was a significant decrease in central vessel density (CVD) and central perfusion density (CPD) values in all regions in acromegaly group compared with controls (p < 0.05). Conclusion Our findings with OCTA show that acromegaly causes a significant capillary network decrease according to the healthy subjects.

Amaç: Göz bankasında speküler mikroskopinin (SM) gerekliliği açısından donör kornea endotel hücre morfolojisinin donörün epidemiyolojik özellikleri ve ölüm zamanı ile ilişkisini değerlendirmek. Gereç ve Yöntem: Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi'ne bağlı Kornea Bankası'nda 2010-2012 tarihleri arasında alınan donör kornealara ait speküler mikroskopi (SM) verileri retrospektif olarak değerlendirildi. Bulgular: Yaş ortalaması 40,11±15,51 yıl olan 606 donörden 1180 adet kornea dokusu alınmıştı ve donörlerin 449'u (%74,1) erkek, 157'si (%25,9) kadındı. Kornea alınma süresi, ölüm saati sonrası ortalama 1,52±0,6 saat idi. Endotel hücre sayısı (EHS) ortalama 2852,07±542,15 hücre/mm 2 olup cinsiyete göre anlamlı bir farklılık yoktu (p>0,05). Yaş gruplarına göre ≤20 yaş donörlerde EHS en yüksekti ve diğer yaş grupları ile arada anlamlı farklılık vardı (p<0,001). Ortalama hücre alanı (OHA) 367,86±86,30 µm 2 ; hegzagonalite oranı (%) 49,29±7,76; değişkenlik katsayısı (DK) 31,52±6,37 olup bu değişkenlerle yaş arasında istatistiksel açıdan anlamlı ilişki mevcuttu (p<0,001). Cinsiyete göre OHA anlamlı farklılık gösterirken (p<0,05); cinsiyet ile hegzagonalite ve DK arasında ilişki saptanmadı (p>0,05). Ölüm saati-kornea alınma saati arasında geçen süreye göre gruplar arasında EHS, OHA, DK ve hegzagonalite değerleri için istatistiksel açıdan anlamlı farklılık izlenmedi (p>0,05). Endotel hücre sayısı <2000 hücre/mm 2 olan donörlerin %79'u ≤60 yaş grubunda yer almaktaydı ve >61 yaş grubundaki donörlerin %78'inde EHS ≥2000 hücre/mm 2 idi. Sonuç: Donör kornea morfolojik parametreleri yaş ile anlamlı ilişki göstermesine rağmen EHS<2000 hücre/mm 2 olan donör dağılımı SM'nin keratoplasti öncesi standart bir işlem olarak kullanılması gerektiğini göstermektedir. (Turk J Ophthalmol 2014; 44: 190-5) Anah tar Ke li me ler: Göz bankaları, keratoplasti, doku vericileri, speküler mikroskopi Objective: To evaluate the correlation between donor cornea endothelial cell morphology, epidemiological features of the donor and time of death in terms of necessity of specular microscopy (SM) in eye bank. Materials and Methods: SM data acquired from Dr. Lütfi Kırdar Kartal Training and Research Hospital Cornea Bank between 2010 and 2012 were retrospectively evaluated. Results: One thousand one hundred eighty cornea tissues were excised from 606 donors. The mean age of the donors was 40.11±15.51 years. Four hundred forty-nine (74.1%) donors were male and 157 (25.9%) donors were female. The mean duration of corneal excision was 1.52±0.6 hours after the time of death. The mean endothelial cell density (ECD) was 2852.07±542.15 cells/mm 2 and there was no significant difference with respect to gender (p>0.05). According to age groups, the endothelial cell density was highest at age 20 years and below, and there was a significant difference compared to the other age groups (p<0.001).The mean cell area (MCA) was 367.86±86.30 µm 2 ; the hexagonality rate was 49.29±7.76 (%); the coefficient of variation (CV) was 31.52±6.37 and there was a stat...

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Objective:To evaluate the changes in anterior segment parameters after neodymium–yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy in 1-piece and 3-piece IOLs.Methods:In an institution, 65 eyes of 65 consecutive pseudophakic patients with posterior capsule opacification underwent Nd:YAG laser capsulotomy. The patients were divided into two groups according to the IOL type. Group-1 consisted of 35 subjects with 1-piece IOL and Group-2 consisted of 30 subjects with 3-piece IOL. Anterior segment parameters were measured with the Sirius rotating camera before, one week and one month after Nd:YAG laser capsulotomy.Results:Mean age was 72.3±5.2 years in 1-piece IOL and 72.3±6.8 years in 3-piece IOL. There were no statistically significant differences before capsulotomy for IOP, axial length, spherical equivalent, anterior chamber depth, central corneal thickness, anterior chamber angle and anterior chamber volume between two IOL groups. BCVA improved after capsulotomy in both groups (p=0.001). Both IOL groups had statistically significant myopic shift compared with the baseline values (P= 0.03 and P=0.01 resp.). Both IOL groups had statistically significant decrease in ACD, from baseline to the 1st week and 1st month (p=0.04 and 0.03 resp.).Conclusion:To achieve the highest percentage of refractive and anterior segment stability surgeons may prefer to implant the 1-piece IOL design.