Background:In Ethiopia, second-line anti-retroviral therapy (ART) for HIV/AIDS patients was started some years ago; however, few studies have reported the unfavorable outcomes of second-line ART. Therefore, this study aimed to assess the incidence and predictors of unfavorable outcomes and their association with change in viral load among adult HIV/AIDS patients on second-line treatment at selected public hospitals in Addis Ababa, Ethiopia. Methods: A retrospective follow-up study was conducted at selected public hospitals in Addis Ababa, Ethiopia, on 421 HIV/AIDS patients on second-line ART from 2016 to 2021. Cox proportional hazard models with a linear mixed effect model were jointly modeled using the JM package of R software with time-dependent lagged parameterizations, and a 95% confidence interval was used to select significant variables. Results: Overall, 89 HIV/AIDS patients developed unfavorable outcomes. The incidence density was 7.48/100 person-years (95% CI:
Backgrounds Micronutrient deficits in women of reproductive age have been linked to poor pregnancy outcomes. The most common micronutrient deficits in women are iron and folate. The World Health Organization recommends daily oral iron and folic acid supplementation (IFAS) as part of routine antenatal care to lower the risk of maternal anemia and adverse pregnancy outcomes. However, the effectiveness of the supplementation relies on client’s strict adherence. The aim of this study was to determine time- to- non-adherence to IFAS and associated factors among pregnant women in Hosanna Town, South Ethiopia. Methods A community based cross sectional study design was employed from May 15-June11, 2021. Data were entered into Epi-Data version 3.1 and exported to SPSS version 23 for analysis. The Cox regression hazard model was applied. The threshold of statistical significance was declared at a p-value <0.05 and adjusted hazard ratios (AHRs) with corresponding 95% confidence intervals were used to report. Result The median time-to-non-adherence was 74 days (95 percent CI: 65.33–82.67). After adjusting for the confounders, age (AHR = 1.05, 95% CI: 1.01–1.09), education status (AHR = 2.43 95%CI 1.34–4.40, AHR 3.00, 95% CI: 2.09–4.31, AHR 1.91, 95% CI: 1.32–2.77), household’s wealth index (AHR = 1.73, 95% CI: 1.19–2.51, AHR = 1.64, 95% CI:1.15–2.35), and counseling at service delivery (AHR = 2.53, 95% CI: 1.88–3.41) were independent predictors of time to non-adherence to IFAS among pregnant women. Conclusion The median time to non-adherence was short and women became non-adherent before the recommended duration. Improving women’s education and counseling pregnant women on IFAS during pregnancy would make a change.
Background: Coronavirus disease 2019 (COVID-19) may affect anybody, and prisoners are a susceptible group in terms of the risk of contracting infectious illnesses owing to a variety of situations such as overcrowding, confinement, and poor cleanliness. Therefore, this study aimed to assess prisoners’ Knowledge, Attitude, and Practice (KAP) of COVID-19 and its determinants in southern Ethiopia. Method: The Institutional cross-section study was conducted among 404 prisoners selected using simple random sampling obtained from the prisoner’s registration book. To collect data from prisoners, an interviewer-based face-to-face data-collecting technique was used. Multivariate ordinal logistic regression was used to identify determinants of KAP toward COVID-19. Results and Conclusions: The majority of the prisoners had limited understanding and poor preventive strategies application toward COVID-19. Being male, living in a rural area, having a low educational standing, and being a farmer were related to limited knowledge, negative attitude, and poor practice toward COVID-19. Furthermore, having little understanding was linked with poor practice toward COVID-19. As a result, the focus should be on convicts, creating awareness, and addressing specific socioeconomic features of prisoners, as well as boosting COVID-19 preventive activities that should get attention in the prison.
Background Health equity has emerged as a global issue in the post-2015 Sustainable Development Goals, and Ethiopia is no exception. Despite positive improvements, inequities in maternal health service utilization among demographic groups continue to be one of Ethiopia's significant challenges. This study focuses on antenatal care service discrimination among a local underprivileged group of women known as the "Golden Hands" community in Ethiopia's Kembata Tembaro Zone. The subgroup community consists of underprivileged women “Golden-hands," formerly known as "Fuga," who face discrimination in all aspects of life owing to their living conditions and ethnic background. Methods A community-based comparative cross-sectional study was conducted in the Kembata-Tembaro zone of Southern Ethiopia. Double population proportion sample size estimation method was used and a total of 1,210 eligible participants were included in the study, out of which 440 of were Golden-Hands community members. Stratified random sampling was used to choose the samples. The concentration curve and index, as well as multivariable decomposition analysis, were used to examine inequality. Result Discrimination accounted for 60.23 percent of the decreased ANC service use by the Golden Hand community and Endowment accounts for just 39.47 percent of the reduced ANC service. The rate of ANC service is 3.64 times greater in women in the top quintile than in those in the lowest. increasing in age, urban residence, and wealth index were the most important independent factors with statistically significant contributions to discriminated difference. Conclusion High disparity in ANC service was observed in the study and, residency and wealth index contribute the highest proportion to the inequity. Therefore, marginalized groups in society people should get higher attention by policymakers and other organization.
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