With a massive influx of multimodality data, the role of data analytics in health informatics has grown rapidly in the last decade. This has also prompted increasing interests in the generation of analytical, data driven models based on machine learning in health informatics. Deep learning, a technique with its foundation in artificial neural networks, is emerging in recent years as a powerful tool for machine learning, promising to reshape the future of artificial intelligence. Rapid improvements in computational power, fast data storage, and parallelization have also contributed to the rapid uptake of the technology in addition to its predictive power and ability to generate automatically optimized high-level features and semantic interpretation from the input data. This article presents a comprehensive up-to-date review of research employing deep learning in health informatics, providing a critical analysis of the relative merit, and potential pitfalls of the technique as well as its future outlook. The paper mainly focuses on key applications of deep learning in the fields of translational bioinformatics, medical imaging, pervasive sensing, medical informatics, and public health.
With the increasing demands on quality healthcare and the raising cost of care, pervasive healthcare is considered as a technological solutions to address the global health issues. In particular, the recent advances in Internet of Things have led to the development of Internet of Medical Things (IoMT). Although such low cost and pervasive sensing devices could potentially transform the current reactive care to preventative care, the security and privacy issues of such sensing system are often overlooked. As the medical devices capture and process very sensitive personal health data, the devices and their associated communications have to be very secured to protect the user's privacy. However, the miniaturized IoMT devices have very limited computation power and fairly limited security schemes can be implemented in such devices. In addition, with the widespread use of IoMT devices, managing and ensuring the security of IoMT systems are very challenging and which are the major issues hindering the adoption of IoMT for clinical applications. In this paper, the security and privacy challenges, requirements, threats, and future research directions in the domain of IoMT are reviewed providing a general overview of the state-of-the-art approaches.
Electroencephalographic signals (EEG) have widely used in medical applications, yet the use of the signals as biometric identifier has only gained interests in the last few years. The advantage of EEG-based biometric recognition lie in its dynamic property and uniqueness among different individuals. However, it is for this reason that manually designed features are not always adapted to the needs. A novel approach based on 1D Convolutional Long Short-term Memory Neural Network (1D-Convolutional LSTM) for EEG-based biometric identification is proposed in this paper. The complementarity of CNNs and LSTMs largely improves the performance of the identification by removing variation of the input, facilitating the temporal modeling and transforming the features into the high dimensional space which makes the classification more effective respectively. We investigate the architecture to determine the appropriate topology to improve the efficacy of the 1D-Convolutional LSTMs for the authentication. The performance of the proposed approach was validated with a public database consists of EEG data of 109 subjects. The experimental results showed that the proposed network has a very high recognition rate of 99.58%, when using only 16 channel EEG signals, which outperforms the state-of-the-art EEG-based biometric identification methods.
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