Quadriceps femoris thickness decrease, proposed as a surrogate for muscle mass, is an early, frequent, and intense phenomenon in PICU. Quadriceps femoris ultrasonography is a reliable technique to monitor this process and in future could help to guide rehabilitation and nutrition interventions.
Objectives:
Malnutrition and faltering growth at PICU admission have been related to suboptimal outcomes. However, little is known about nutritional status deterioration during PICU stay, as critical illness is characterized by a profound and complex metabolism shift, which affects energy requirements and protein turnover. We aim to describe faltering growth occurrence during PICU stay.
Design:
Single-center prospective observational study.
Setting:
Twenty-three-bed general PICU, Lyon, France.
Patients:
All critically ill children 0–18 years old with length of stay longer than 5 days were included (September 2013–December 2015).
Interventions:
Weight and height/length were measured at admission, and weight was monitored during PICU stay, in order to calculate body mass index for age z score. Faltering growth was defined as body mass index z score decline over PICU stay. Children admitted during the first year of the study and who presented with faltering growth were followed after PICU discharge for 3 months.
Measurements and Main Results:
We analyzed 579 admissions. Of them, 10.2% presented a body mass index z score decline greater than 1 sd and 27.8% greater than 0.5. Admission severity risk scores and prolonged PICU stay accounted for 4% of the variability in nutritional status deterioration. Follow-up of post-PICU discharge nutritional status showed recovery within 3 months in most patients.
Conclusions:
Nutritional deterioration is frequent and often intense in critically ill children with length of stay greater than 5 days. Future research should focus on how targeted nutritional therapies can minimize PICU faltering growth and improve post-PICU rehabilitation.
Intensive care unit professionals have experience in critical care and its proportionality, collegial decision-making, withholding or withdrawal of treatment deemed futile, and communication with patients’ relatives. These elements rely on ethical values from which we must not deviate in a pandemic situation. The recommendations made by the Ethics Commission of the French Intensive Care Society reflect an approach of responsibility and solidarity towards our citizens regarding the potential impact of a pandemic on critical care resources in France, with the fundamental requirement of respect for human dignity and equal access to health care for all.
Surgical site infections (SSI) increase length of stay, morbidity, mortality and cost of hospitalization. Staphylococcus aureus (SA) carriage is a known risk factor of SSI in adults, but its role in pediatrics remains uncertain. The main objective of this pilot prospective monocentric cohort study was to describe the prevalence of SA colonization in children under 1 year old before cardiac surgery. The secondary objectives were to compare the incidence of SSI and other nosocomial infections (NI) between preoperative carriers and non-carriers. From May 2012 to November 2013, all children <1 year old undergoing cardiac surgery under cardiopulmonary bypass underwent preoperative methicillin-resistant (MRSA) and methicillin-sensitive SA (MSSA) screening using real-time PCR. The only exclusion criterion was invalid PCR. All patients were followed up to 1 year after the surgery regarding SSI and other nosocomial infections. Among the 68 studied patients, SA colonization prevalence was 26.5%, comprising 23.5% MSSA and 2.9% MRSA. There was no significant difference between colonized and non-colonized children regarding SSI rate (16.7 vs 20%; p = 0.53), but ventilator-associated pneumonia rate was significantly higher among the SA carriers (22.2 vs 2%; p < 0.05). The colonization rate was different depending on the age of the patients (p < 0.05). This pilot study highlights that colonization with MSSA is frequent whereas MRSA prevalence is low in our population. In this cohort, there was no association between SA colonization and SSI incidence but further studies are needed to analyze this association.
La décision est au cœur du métier de réanimateur. Elle est partie intégrante de son activité au quotidien. Cet exercice s’avère d’autant plus difficile lorsque, en période de crise sanitaire, les médecins sont confrontés à une majoration du flux des patients en inadéquation avec la capacité d’accueil en réanimation. Il est nécessaire de s’interroger sur les mécanismes qui entrent en jeu dans cette démarche de décision. L’analyse étymologique aide à une meilleure compréhension de ces mécanismes. Décider n’est pas choisir. On ne peut réduire la décision à un calcul mathématique. L’angoisse, l’incertitude font partie intégrante de ce processus. Les récents travaux sur les biais cognitifs ainsi que la recherche en neurosciences ont mis l’accent sur sa profonde complexité. Le partage de décision, exercice bien développé en soins critiques, permet de soulager en partie du fardeau qu’elle représente. Si les avantages de ce partage sont indéniables, il ne faut pas en négliger ses inconvénients. Elle reste un fardeau indispensable car témoin de l’engagement du soignant envers le soigné et de l’expression de sa responsabilité morale. Le fardeau est une charge que l’on porte, que l’on assume. S’il pèse dans la décision, il lui apporte aussi toute sa valeur. Décider c’est soigner. L’avènement de nouvelles technologies pourrait considérablement modifier l’approche décisionnelle. Il est nécessaire, en amont, de définir ce que représente la décision en réanimation afin d’intégrer au mieux ces technologies sans se positionner comme technolâtre ou technophobe mais plutôt technosophe.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.