A 67-year-old man from Jingzhou was admitted to the First Hospital Affiliated to Yangtze University in July 2013 with sudden onset of abdominal pain with dizziness for 12 h. The patient had sign of peritoneal irritation. Ultrasonography of the abdomen and pelvis showed hepatic fibrosis due to schistosomiasis. Computed tomography showed free gas in the peritoneal cavity. Plain abdominal radiography showed bilateral subdiaphragmatic accumulation of gas, perforation of the viscus, and radio-opacity in the left renal area. The patient underwent emergency exploratory laparotomy. At laparotomy, a moderate amount of muddy yellow pus was found in the intra-abdominal cavity. At the junction of the jejunum and ileum, about 250 cm from Treitz's ligament, there was an about 10-cm length of inflamed small bowel with perforation (3 mm in diameter) along the mesenteric border at the middle of the lesion. The patient underwent resection of the affected intestinal segment, along with end-to-end intestinal anastomosis. Histopathological examination revealed mucosal necrosis and hemorrhage with a large number of infiltrating eosinophils and neutrophils, and acute submucosal inflammation with a large number of infiltrating eosinophils and neutrophils associated with Schistosoma japonicum (S. japonicum) eggs. No intravascular adult parasite was found. Postoperatively, the patient was treated with praziquantel (30 mg/kg daily) for 4 d. The patient progressed well. To the best of our knowledge, this is the first case of small bowel perforation associated with eggs of S. japonicum.
Objective: To explore the safety and the short-term curative effect of the application of assisted laparoscopic radical resection for the mid transverse colon cancer. Methods: A retrospective analysis of 25 cases clinical data of radical resection of mid transverse colon cancer from March 2006 to March 2014 in our hospital. Cases were divided into two groups, laparoscopic group with 12 cases and open group with 13 cases. Intra-operative observation indexes (operation time, bleeding volume, the number of dissected lymph nodes), post-operative recovery indexes (flatus time, liquid food intake time, ambulation time, hospitalization time), post-operative complication (incision site infection, abdominal bleeding, intra-abdominal infection, anastomotic fistula, intestinal obstruction and re-hospitalization within 30 days, mortality) and patient's five-year overall survival were observed in two groups. Results: Operation methods including the principle of complete mesocolic excision (CME), colon dissection along the anatomical plane and safe anastomosis method were applied in Laparoscopic group. Average surgery time of Laparoscopic group was longer than open group, but there was no statistically significant difference between the two groups (p > 0.05). Intra-operative blood loss in the Laparoscopic group was obviously lower than open group; the difference was statistically significant (p < 0.05). The number of lymph node dissection in laparoscopic group was higher than open group (p < 0.05). Laparoscopic group in the postoperative recovery index including recovery of bowel function, ambulation time and hospitalization time was shorter than that of the open group after operation (P < 0.05). Conclusion: The use of laparoscopic radical resection for the mid transverse colon cancer resulted in acceptable short term curative effects.
A 67-year-old woman presented with abdominal distension and difficulty in defecation. She had a huge mass in the left lower abdomen and hyperamylasemia with normal pancreatic-type amylase (P-AMY). Nuclear magnetic resonance and computed tomography scan revealed a huge pelvic mass, but the origin of mass wasn't certain. After discussion with the multidisciplinary team, ultrasonography guided pathological biopsy of the mass was done. Pathological biopsy showed that the mass was poorly differentiated adenocarcinoma, which may be originated from ovary. Patient was on neo-adjuvant chemotherapy. After one and a half months of chemotherapy, the patient developed colorectal-reproductive system fistula with hyperpyrexia. Laparatomy with resection of mass, sigmoid colon, left ovary and part of uterus, proximal colostomy with closure of the distal rectum and end to end anastomosis of left ureter with DJ tube drainage (left ureter invaded by tumor confirmed intra operation) was done. Operative finding: Fistula between sigmoid colon and uterus through the tumor.
In this study, through employing the mixed-ligand synthesis method, a novel coordination polymer (CP) containing Cu(II) has been synthesized in success with the reaction of 4-bmbpd and Cu(NO 3 ) 2 ⋅3H 2 O in the presence of auxiliary polycarboxylate ligand 1,3,5-H 3 BTC under hydrothermal conditions, and the chemical formula of this compound is [Cu(4-bmbpd)(1,3,5-HBTC)]⋅2H 2 O (1) (1,3,5-H 3 BTC is 1,3,5-benzenetricarboxylic acid and 4-bmbpd is N,N′-bis(4-methylenepyridin-4-yl)-1,4-benzenedicarboxamide). The assessment of its prevention and predictive nursing activity on the hypothermia during laparoscopic cholecystectomy operation was conducted and the corresponding mechanism was studied simultaneously. The molecular docking simulation helps for identifying that the carboxylate group and the amide group form multiple H-bonds with respect to the active sites within the docking pocket of the target protein.
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