The study was carried out to evaluate the effect of feeding locust bean (Parkia Biglobosa) seed meal (LBSM) at graded levels on the performance of broilers. Two hundred and forty broilers were used which were randomly allotted to four treatment groups, each replicated four times in a completely randomized design. The diets contained 0% level of LBSM which served as the control, while other three diets contained 5, 10 and 15% levels of LBSM. The experiment lasted for 28days. Significant differences of (P<0.05) were observed in feed intake (g/b/d) water intake ml/b/d, final body weight (g/b), body weight gain (g/b) averaged daily gain (g/b/d) and feed conversion ratio (FCR). While no significant effect of locust bean seed meal (LBSM) in broilers diets provide effective mechanism for better performance. But live weight was significantly influenced (P<0.05) by LBSM. Analysis of variance (ANOVA) was used to determine significant difference between treatment groups in term of performance parameters. Where significant difference existed, Duncan’s multiple range test was applied to separate the means. Data analysis was carried out using (SPSS (SPSS, 2013version 20.0).It is concluded that LBSM can be included in the diet of broilers at starter phase from 5-15% inclusion levels while at finisher phase, diets containing 10 and 15% level of inclusion would be used for better performance without any deleterious effect on the growth performance. It could be recommended that, diets containing 10 and 15% LBSM level of inclusion would be used for better performance and economic benefit with better feed conversion ratio.

Chloramphenicol a broad spectrum antibiotic was tested on broiler birds to evaluate the effect of its prolonged administration on heamatological parameters, identification of histopathological changes on organs (Liver, Spleen and Kidneys) and to determine if prolonged effect has effects on weight gain and mortality rate. One hundred and twenty day old chicks from Kamadex Ibadan were used for the experiment. The birds were assign to two (2) treatments and control group each replicated in a Complete Randomized Design (CRD), birds in treatment one (T1) were administered normal dose of Chloramphenicol (250 mg/Kg), while treatment two (T2) were served with triple dose in medicated water served ad-lib for seven weeks, while the control (T3) were served with un-medicated water ad-lib. Samples (blood, liver, kidney and spleen) were collected and analyzed after 8 weeks of the experiment. Birds showed significant variations in heamatological values across treatments. Lymphocysts count: treatment two (T2) was higher than the treatment one (T1) whereas that of (T3) was found to be less, compared to those of T1 and T2. Heterophils: T3 was higher than the T1 while that of T2 was less as compared to T3 and T1. Basophil: T1 was higher than T3 while that of T2 was less. A lower value was observed in weight gain with birds on T2 as compared to T1 and T3. The liver of birds on T1 and T2 were significantly larger than those on T3. High mortality was recorded in birds on T2 compared to those in T3 and T2. The histopathological pictures of the liver, kidney and the Spleen depict a varying degree of necrosis and hemorrhagic foci on all the organs, the changes were much severe on T2 as compared to those of T1 and T3.