Pure small cell carcinoma of the prostate (SCPCa) is a very rare condition usually with poor survival after diagnosis. It seems to show different clinical features compared to other prostate cancer subtypes, specifically adenocarcinoma. Here, we present a 74-year-old man early diagnosed with SCPCa treated with a cisplatine and etoposide regimen. There was no metastasis found in imaging studies and bone scan. The patient mostly complained of obstructive symptoms which were relieved after resection. Interestingly, our patient experienced a disease free condition after chemotherapy and no further progression was found. This could implicate the critical role of early diagnosis in the treatment of SCPCa despite its aggressive nature.
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