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The skin of the eyelids is particularly vulnerable to eczema and dermatitis for a combination of reasons which do not apply to any other part of the skin surface. The eyelid epidermis is very thin so that it may react to primary irritants and to sensitizing agents when other parts of the skin would be resistant. The eyelids are exposed more than most parts of the skin to irritant vapours and also to substances carried there by the fingernails and by the well-protected palmar aspects of the fingers and, furthermore, the eyelids are frequently rubbed by the hands when patients are tired or emotionally upset. Seborrhceic dermatitis commonly involves the eyelids and this disease is characterized by extreme sensitivity to irritants and also to infection.