Antioxidants are an important group of medicinal preventive compounds as well as being food additives inhibiting detrimental changes of easily oxidizable nutrients. The present investigation has been carried out to evaluate the antioxidant properties of different solvent extracts of Agriophyllum pungens seeds by various in vitro systems. The anti-oxidative activities of these samples were determined using four methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, ferric-reducing antioxidant potential (FRAP), and hydroxyl (OH) radical scavenging activities. Additionally, total flavonoids and phenolic contents (TPC) were also determined. Yield of extracts varied widely among solvents and was the highest for water extract (5.642% based on dry weight basis), while ethyl acetate extract exhibited the highest total phenolic content (0.149 mg/mL), total flavonoid content (0.111 mg/mL), and antioxidant activities (P<0.05). The ABTS radical scavenging activity of A. pungens seeds occurred in the following order: ascorbic acid (92.9157%)>BHA (90.1503%)>α-tocopherol (87.7527%)>APEA (83.9887%) >APWR (75.5633%); the antioxidant activity of the extracts might be attributed to the presence of these phenolics. This suggests that A. pungens seed extract is a potential source of natural antioxidants, which could be added to dietary supplements to help prevent oxidative stress.
Ribes diacanthum Pall (RDP) is a member of the Saxifragaceae family. The plant is traditionally used in Mongolia for the treatment of various ailments associated with kidney and bladder’s diseases, cystitis, kidney stone, and edema. This study was aimed to investigate antioxidant activities of different solvent extracts of whole Pall plants, based on ferric-reducing antioxidant potential (FRAP), 2,2′-azinobis(3-ethybenzothiazoline-6-sulfonic acid) (ABTS· +) radical scavenging activity, 1,1-diphenyl-2-picrydrazyl (DPPH·), and hydroxyl (·OH) radical scavenging activities. Additionally, total flavonoids and phenolic contents (TPC) were also determined. The ethyl acetate extract of RDP (EARDP) had a remarkable radical scavenging capacity with an IC50 value of 0.1482 mg/mL. In addition, EARDP was shown to be higher in total phenolic and flavonoid contents than the methanol extract of RDP (MRDP). Moreover, the EARDP had the predominant antioxidant capacity, DPPH, hydroxyl, and ABTS radical scavenging activities and ferric reducing power. These results suggest a potential for R. diacanthum Pall extract as a functional medicinal material against free-radical-associated oxidative damage.
Many herbs have been used therapeutics in Mongolian traditional medicine. Ribes Diacanthum Pall (Tehiin sheeg) is an important medicinal plants native to Mongolia. Areal parts of the plant are used in Mongolian folk medicine for the treatment of kidney and bladderˈs diseases, cystitis, kidney stones, watery edema, to stimulate the diuretic effect and reducing the toxic. However, antioxidant information on these plants has not been available. The antioxidant potency of methanolic extract of Ribes Diacanthum Pall (MRDP) was investigated by employing various in vitro systems, such as total polyphenolic contents, 1,1‐diphenyl‐picrylhydrazyl (DPPH) free radical, ABTS and hydroxyl (•OH) radical scavenging activities, and ferric reducing power assay. Higher levels of total phenolics ( 0.518 mg/ml extract) and flavonoids ( 0.390mg/ml) were observed in methanolic extract of areal parts. Moreover, this extract had the predominant antioxidant capacity, DPPH (IC50: 8.7046mg/ml ), hydroxyl radical scavenging activities (IC50: 9.3268mg/ml) and ferric reducing power (0.3161mg/ml), as well as ABTS radical scavenging activity (92.054% 10mg/ml). In addition, MRDP showed strong ability on ferric reducing power (0.3161mg/ml ). Overall, results suggested MRDP might be beneficial as a potent antioxidant effectively employed as an ingredient in functional food applications and information for understanding pharmacological effects of this herbs.
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