Background Breast asymmetry is a prevalent mammographic finding described in BI-RADS atlas as asymmetry, focal asymmetry, global asymmetry, and developing asymmetry. Mammography has a limited role in discrimination between benign and malignant asymmetry, and digital mammography can overlook up to 15–30% of breast tumors. The purpose of our study was to assess the role of contrast-enhanced mammography (CEM) in distinction between benign and malignant asymmetries. Results Out of the studied 540 indeterminate and suspicious asymmetries, and according to final histopathological results, 97/540 (17.9%) asymmetries were benign, 395/540(73%) asymmetries were malignant, 48/540 (8.9%) asymmetries were normal with no underlying pathology. After comparing results of sonomammography and CEM, CEM showed higher sensitivity (96.5% vs. 85.8), specificity (77.1% vs. 64.4%), NPV (88.8% vs. 62.7%), PPV (92.04% vs. 86.7%) and accuracy (91.3% vs. 80%). Conclusions CEM has proven to be a valuable and beneficial imaging technicality for patients and radiologists, with breast cancer detection sensitivities superior to that of full-field digital mammography (FFDM) with ultrasonography (US).
Objectives: To describe the diagnostic performance of dynamic contrast enhanced MRI in differentiating between benign and malignant breast lesions. Methods: the study was conducted on 40 patients with 40 lesions. MR examinations were performed using a closed MRI machine with magnets of intensity field 1.5 Tesla system,equipped with bilateral dedicated breast coils. All lesions were biopsied considering histopathologic findings as the standard of reference. Probability of malignancy was assessed according to BI-RADS for DCE-MRI. Diagnostic accuracy of DCE-MRI was statistically analyzed. Results: Regarding to the final outcome of the reviewed 40 MRI studies depending on the histopathological results accepted as standard reference, histopathology revealed malignancy in 67.5 % of lesions (27/40) and DCE-MRI showed sensitivity (96.3%) and specificity (76.9%) Conclusions: Dynamic contrast enhanced MRI facilitates differentiating benign and malignant breast lesions.
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