Electrosurgery is one of the advances in the surgical field and used commonly. Modern electrosurgical units considered relatively safe. Although rare, inadvertent skin burns due to electrosurgery caused by different mechanisms were reported in the literature. Positioning the patient in prone is required for some surgeries and utilizing this position in a proper manner is essential to avoid complications. We present a case of a 47-year-old female patient who underwent uneventful spinal surgery in a prone position. The patient complained of pain in fingers postoperatively that revealed third-degree skin burn. Plastic surgery was involved in the treatment of burns and the patient followed regularly until fully healed. This case study aims to prompt awareness among surgeons and the staff of the operation-room regarding the unintended burn of patients caused by aberrant circuit related to electrosurgery in prone position.
Autism spectrum disorder (ASD) known as a set of behavioral and neurocognitive problems that are identified by challenges in difficulties interacting and communicating with others, as well as heightened repetitive and/or restrictive behaviors. Elevated immune reaction and enhancements in pro-inflammatory cytokines have been discovered in the brains of those who have ASD. A recent article associated autism with abnormalities in mitochondrial respiratory control. Based on various studies, mitochondrial dysfunction is caused by oxidative stress, inadequate nutrition, insufficiency of vitamins, compromised immune system, contact with harmful environmental substances, and modified calcium signaling. Polyphenols found in our diet are active compounds that have the potential to prevent and treat various chronic illnesses including, neurodegenerative and neurodevelopmental problems. This is mainly due to their ability to regulate crucial pathways that cause inflammation and oxidation in the body. The application of polyphenols may result in a reduction of neuroinflammation, facilitating an improvement in the manifestations of ASD. This review focused on the preclinical and clinical studies that documented the beneficial impacts of diet related for the modulation of ASD.
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