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Aim Acute poisoning is one of the major topics in emergency medicine practices. Despite the recent developments in toxicology, technological advances and changing lifestyles reveal new factors, and poisoning cases remain to be a problem. All poisonings should be considered serious and independent from their clinical presentation at the time of admission. Identifying the cause and prompt initiation of treatment is life-saving. Causes of poisoning vary between countries and different regions of the same country. In the present study, cases admitted to the Emergency Department of Internal Medicine at Haseki Training and Research Hospital were evaluated and causes of acute poisoning were investigated. Subject and methods Medical records of 675 cases of acute poisoning were retrospectively evaluated in the present study.Results The mean age of 675 cases included was 29.24± 13.71 years of age of which 66.4% were women. Drugs were the most common cause of poisoning (74.2%), which was followed by carbon monoxide (8.7%) and alcohol (8.4%) poisoning. Poisoning was deliberate in 73.5% and accidental in 25.6% of the cases. Treatment in intensive care unit was required in 6.6% of the patients. Conclusion Knowing the causes of poisonings will be beneficial in management approach and determining prevention strategies. Increased awareness of health professionals and public about regional causes of poisoning and prevention strategies will reduce morbidity and mortality associated with acute poisonings.

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Objective: Pulmonary complications are common in patients with liver cirrhosis.Devolopment of pulmonary hypertension (PH) is associated with a poor prognosis in these patients. Pulmonary arterial stiffness (PAS) is considered an early sign of pulmonary vascular remodeling. The aim of this study is to investigate PAS and compare it with right ventricular (RV) functions in patients with cirrhosis who are scheduled for liver transplantation. Methods:The study included 52 cirrhosis patients (mean age 51.01 ± 12.18 years, male gender 76.9%) who were prepared for liver transplantation and 59 age and sex matched (mean age 51.28 ± 13.63 years, male gender 62.7%) healthy individuals.Patients with left ventricular ejection fraction (LVEF) less than 55%, ischemic heart disease, more than mild valvular heart disease, chronic pulmonary disease, congenital heart disease, rheumatic disease, moderate to high echocardiographic PH probability, rhythm or conduction disorders on electrocardiography were excluded from the study. In addition to conventional echocardiographic parameters, PAS value, pulmonary vascular resistance (PVR) and RV ejection efficiency was calculated by the related formulas with transthoracic echocardiography (TTE).Results: Demographic characteristics and cardiovascular risk factors of the groups were similar. PAS, PVR, and sPAP values were found to be significantly higher in the

VD plays an important role in health and many diseases notably by affecting the regulation of cell growth, inflammation, and the immune system. 1 VD stimulates innate immune cells such as macrophages to secrete anti-microbial peptides. 2 VD also controls adaptive immunity as the expression of >100 genes in T cells is altered by the interaction of VD and VD receptors in T cells. [3][4][5][6][7] For instance, VD increases IL-10 and FOXP3 expressing regulatory T cells, regulating both innate and adaptive immunity. 8 Observational studies have demonstrated that >50% of pediatric populations, that are healthy, had VD insufficiency, and only a minority was taking VD supplements. As low VD status is linked with several diseases, sustaining optimal VD levels by VD supplementation

Various researchers have investigated the personality correlates of defensive and assertive self‐presentation. Yet, only a few studies go beyond the direct relationships and examine the underlying mechanism. The current study examines whether the social comparison orientation (SCO) mediates the relationship between personality and self‐presentation. We also tested whether our proposed model is invariant across genders. We collected data from 496 individuals using the HEXACO personality inventory, the self‐presentation tactic scale, and Iowa–Netherlands SCO scale to test these hypotheses. The path analysis indicated that the partial mediation model provides the best fit to the data (root‐mean‐square error of approximation [RMSEA] = 0.08, comparative fit index [CFI] = 0.97, standardized root mean squared residual [SRMR] = 0.026). While honesty‐humility (β = −0.43) had the strongest total effect on assertive self‐presentation, emotionality (β = 0.34) had the strongest total effect on defensive self‐presentation among other HEXACO dimensions. Additionally, we conducted a multigroup path analysis to test the structural invariance, and the findings indicate that the relationships are invariant across women and men (Δχ2[14] = 11.83, p = 0.61). These findings suggest that the association between personality and self‐presentation might not be straightforward. The findings are discussed in relation to facet and factor level associations among the variables, self‐presentation strategies, and gender roles.