This paper explores the effect on pair-task performance of test-takers’ familiarity with their partner. O’Sullivan (2000a), like McNamara (1996), sees test performance as being affected by a number of factors, related to the test-taker, the interlocutor and the task. Evidence from the psychology literature, and anecdotal evidence from language learners and teachers, suggests that familiarity with one’s partner in an interactive task might positively affect performance, although in the only published study to date, Porter (1991a) found no evidence to support this hypothesis. A group of 32 Japanese learners performed a series of three tasks (personal information exchange, narrative, and decision making), once with a friend, and again with a person who was not known to them. All performances were video-recorded, awarded scores by trained raters and transcribed for analysis. Results suggest evidence of an `acquaintanceship’ effect, with subjects achieving higher scores when working with a friend. However, analysis of the language suggests that there is no effect on linguistic complexity, and that there is a sex-ofinterlocutor by acquaintanceship interaction effect for accuracy. These results appear to support findings in the literature on second language acquisition, which suggest that learners vary their language when interacting with familiar or unfamiliar speakers (Plough and Gass, 1993; Tarone and Liu, 1995), although they contradict the findings of Porter (1991a). Despite its limitations, the results of this study confirm that any test format that employs tasks requiring interaction between individuals is in need of urgent and extensive study.
Porous collagen-glycosaminoglycan (collagen-GAG) scaffolds have shown promising clinical results for wound healing; however, these scaffolds do not replace the dermal and epidermal layer simultaneously and rely on local endogenous signaling to direct healing. Functionalizing collagen-GAG scaffolds with signaling factors, and/or additional matrix molecules, could help overcome these challenges. An ideal candidate for this is platelet-rich plasma (PRP) as it is a natural reservoir of growth factors, can be activated to form a fibrin gel, and is available intraoperatively. We tested the factors released from PRP (PRPr) and found that at specific concentrations, PRPr enhanced cell proliferation and migration and induced angiogenesis to a greater extent than fetal bovine serum (FBS) controls. This motivated us to develop a strategy to successfully incorporate PRP homogeneously within the pores of the collagen-GAG scaffolds. The composite scaffold released key growth factors for wound healing (FGF, TGFβ) and vascularization (VEGF, PDGF) for up to 14 days. In addition, the composite scaffold had enhanced mechanical properties (when compared to PRP gel alone), while providing a continuous upper surface of extracellular matrix (ECM) for keratinocyte seeding. The levels of the factors released from the composite scaffold were sufficient to sustain proliferation of key cells involved in wound healing, including human endothelial cells, mesenchymal stromal cells, fibroblasts, and keratinocytes; even in the absence of FBS supplementation. In functional in vitro and in vivo vascularization assays, our composite scaffold demonstrated increased angiogenic and vascularization potential, which is known to lead to enhanced wound healing. Upon pro-inflammatory induction, macrophages released lower levels of the pro-inflammatory marker MIP-1α when treated with PRPr; and released higher levels of the anti-inflammatory marker IL1-ra upon both pro-and anti-inflammatory induction when treated with the composite scaffold. Finally, our composite scaffold supported a co-culture system of human fibroblasts and do Amaral et al. PRP Incorporation Into Collagen-Based Scaffold keratinocytes that resulted in an epidermal-like layer, with keratinocytes constrained to the surface of the scaffold; by contrast, keratinocytes were observed infiltrating the PRPfree scaffold. This novel composite scaffold has the potential for rapid translation to the clinic by isolating PRP from a patient intraoperatively and combining it with regulatory approved scaffolds to enhance wound repair.
Performance in tests of spoken language can be influenced by a wide range of features of both task and participants. This article hypothesizes that there may be effects on performance attributable to an interaction of variables such as the task topic, the gender of the person presenting the topic and the gender of the candidate. In contrast to previous studies, which have examined speaking tests involving face-to-face interaction, this study considered the issue in a tape-mediated test delivered in a language laboratory, with no inter-locutor present, but where stimulus material is presented by one or more speakers, one of whom acts as ‘audience’ for the candidate’s speech. The test was taken by 894 students graduating from Hong Kong universities. In an advice-giving task, the last of a series involving different situations and audiences, topics considered stereotypically ‘male’-oriented or ‘female’-oriented were presented with systematic changes in the roles taken by the male and female speakers. A multi-faceted Rasch analysis examined the interaction of test-taker gender, task topic, and gender of presenter/audience. The results showed small effects for some, but not all, of the hypothesized interactions. Examples of differential performance by male and female candidates on other tasks are also presented. The article concludes with discussion of the implications for task design and test content.
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